This paper proposes a model for Local Development of the Textile Industry in Tulancingo region in order to make a link between Company-Universidad Politécnica de Tulancingo; under the approach of knowledge network. The research methodology is exploratory, descriptive type with nested design, including the steps of collecting data with SPSS and ATLAS Ti software. The overall objective is to design a model for local development of Textile Industry of the Tulancingo region with a focus on knowledge network between the textile industry in the region and the Universidad Politécnica de Tulancingo as organizational structure, based on the condition of the employer Tulancinguense; for the competitiveness of the industry. For this study establishes the following objectives: develop a business assessment to identify those organizational factors that facilitate learning of the textile industry, to identify common interests of entrepreneurs, shaping the collaborative networking of knowledge in the relationship business-university. The dynamic of the model is targeted at exchanging various aspects of knowledge, strategies, technologies and skills that will build local learning, and the development of the textile industry in Tulancingo region.