2014
DOI: 10.5455/medarh.2014.68.6-9
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Response of Smooth Bronchial Musculature in Bronchoconstrictor Substances in Newborn with Lung Atelectasis at the Respiratory Distress Syndrome (RDS)

Abstract: Objective:Role of the atelectasis (hypoxia) in the respiratory system of the live and exited newborn (250 up to 3000 g. of body weight), which has died due to different causes was studied in this work.Methods:Response of tracheal rings to dopamine, serotonine and ethanol in the different molar concentrations (dopamine: 0,05 mg/ml, 0,5 mg/ml, 5 mg/ml; serotonine (5-HT): 10-4, 10-3, 10-2, 10-1 mol/dm3; ethanol: 0,2 ml, 0,5 ml, 1,0 ml; 96%) was followed up. Study of the smooth tracheal musculature tone (STM) was … Show more

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“…Through the Merkel-neurite complex (MNC), Merkel's disc stimulation can release vesicles containing glutamate, serotonin, substance P, vasoactive intestinal peptide, and calcitonin gene-related peptide (34)-substances that can influence tissue blood circulation, local and pulmonary hemodynamics, and smooth musculature activity (35)(36)(37). Interestingly, Merkel's discs are increasingly recognized to have neuroendocrine activity (38): some of the neuropeptides they release can indeed trigger the B system (28).…”
Section: Changes In Body Tissuesmentioning
confidence: 99%
“…Through the Merkel-neurite complex (MNC), Merkel's disc stimulation can release vesicles containing glutamate, serotonin, substance P, vasoactive intestinal peptide, and calcitonin gene-related peptide (34)-substances that can influence tissue blood circulation, local and pulmonary hemodynamics, and smooth musculature activity (35)(36)(37). Interestingly, Merkel's discs are increasingly recognized to have neuroendocrine activity (38): some of the neuropeptides they release can indeed trigger the B system (28).…”
Section: Changes In Body Tissuesmentioning
confidence: 99%