“…We read with great interest the paper "Accuracy of dynamic preload variables for predicting fluid responsiveness in patients with pediatric liver cirrhosis: A prospective study" by Chen et al 1 In our opinion, there is another reason for the low prognostic value of dynamic parameters to predict fluid responsiveness (FR) in their study. The children were mechanically ventilated with tidal volume of 8 mL/kg, lower than the 10 mL/kg protocols used in earlier comparable studies, [2][3][4] and currently a lung protective strategy with smaller tidal volume is preferred by some or most anesthesiologists in clinical practice. Furthermore, they used positive end expiratory pressures (PEEP) of 5 cm H 2 O.…”