Response to chemotherapy in a child with primary bronchopulmonary leiomyosarcoma

Ferrari, Andrea; Collini, Paola; Casanova, Michela; Meazza, Cristina; Podda, Marta; Mazza, Elena

doi:10.1002/mpo.10041

Cited by 11 publications

(3 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Since 1950, only 15 pediatric cases of leiomyosarcoma of the respiratory tract have been reported in the English-language literature ( Table 1). [1][2][3][4][5][6][7][8][9][10][11][12][13] These reports documented the disease in 9 males and 6 females, with ages ranging from newborn to 14 years. Clinical symptoms are characterized by cough, fever, wheezing, chest pain, and increasing respiratory difficulty leading to dyspnea.…”

Section: Discussionmentioning

confidence: 99%

Leiomyosarcoma of the main bronchus in a girl: A long‐time survivor with multiple lung metastases

Takeda

Iwao

Ohizumi

et al. 2004

Pediatric Pulmonology

View full text Add to dashboard Cite

Primary leiomyosarcoma of the respiratory tract is a very rare malignancy, especially in childhood, with only 15 cases in patients under 16 years old having been reported. In the present case, the survival period from the onset of symptoms has been over 7 years, despite incomplete resection. Based on the 15 published cases, the prognosis is poorer when the tumor is unresected or incompletely resected, but under favorable circumstances, prolonged survival is possible.

show abstract

Section: Discussionmentioning

confidence: 99%

Leiomyosarcoma of the main bronchus in a girl: A long‐time survivor with multiple lung metastases

Takeda

Iwao

Ohizumi

et al. 2004

Pediatric Pulmonology

View full text Add to dashboard Cite

show abstract

“…The former accounts for 5.8% of all paediatric endobronchial tumors (8) with previous radiation therapy, genetic predisposition and immunological factors as main documented risk factors for its occurrence (9). Leiomyosarcoma is even more sporadic, making up 3.8% of all paediatric forms (8). Adenoid cystic carcinoma shows an aggressive attitude, with local relapse and local lymph nodes metastases (10) but it is infrequently described in children.…”

Section: Malignant Tumorsmentioning

confidence: 99%

Tracheal and bronchial tumors

Varela¹,

Pio²,

Brandigi³

et al. 2016

J. Thorac. Dis.

View full text Add to dashboard Cite

Although primary tracheobronchial tumors are extremely rare in children, recurrent respiratory symptoms resistant to conventional therapy require further investigations to exclude possible malignant obstructive causes. As the matter of fact, early diagnosis may allow minimally invasive surgeries, improving the standard of living and the globally survival rate. The aim of this article is to provide an overview of diagnosis and management of tracheobronchial tumors in the early age, since only few reports are reported in the worldwide literature.

show abstract

“…Histological confirmation of metastatic leiomyosarcoma led us to administer radiotherapy, which failed. It is known that leiomyosarcoma is relatively radioresistant, 4 certainly less responsive to radiotherapy than the more common epithelial malignancies that metastasize to the choroid. Trans‐scleral local resection achieved local tumour control in this case.…”

mentioning

confidence: 99%