Response to Hypercapnia Under Ketamine Anaesthesia

Comparison of diazepam–ketamine and thiopentone for induction of anaesthesia in healthy dogs

“…1977). Furthermore, ketamine does not depress the ventilatory response to hypercapnia (Soliman et al. 1975).…”

“…Ketamine, unlike thiopentone, has minimal e¡ects on respiration in humans with well-maintained intercostal muscle tone and arterial oxygen saturation (Gooding et al 1977). Furthermore, ketamine does not depress the ventilatory response to hypercapnia (Soliman et al 1975). The bene¢cial respiratory e¡ects of ketamine anaesthesia have been demonstrated using computed tomography (Lumb et al 1979).…”

A combination of alfaxalone, medetomidine and midazolam for the chemical immobilization of Rhesus macaque (Macaca mulatta): Preliminary results

“…Ketamine is widely used for sedation of large non‐human primates because of its good safety profile and its relative lack of depression of the cardiovascular system . However, used alone ketamine only produces a cataleptic state more similar to heavy sedation than general anaesthesia .…”

“…Ketamine is widely used for sedation of large non-human primates because of its good safety profile and its relative lack of depression of the cardiovascular system. 2,17,18 However, used alone ketamine only produces a cataleptic state more similar to heavy sedation than general anaesthesia. 1 The addition of either a benzodiazepine or an alpha-2 agonists such as xylazine and medetomidine increases the depth of anaesthesia but can also result in depression of the cardiovascular and respiratory systems.…”

The Use of Propofol Anesthesia for Children Undergoing Cardioversion

“…Ketamine has a rapid onset and, unlike thiopental and midazolam, produces analgesia. Ketamine also causes less ventilatory depression and hypotension in most patients than these agents 3 , 4 . The “emergence delirium” associated with the use of ketamine, however, including visual, auditory, and proprioceptive hallucinations, has limited its use.…”