Responsive disassembly of the gold nanoparticle aggregates triggered by the competitive adsorption for lighting up the colorimetric sensing

Antioxidant capacity index based on gold nanoparticles formation. Application to extra virgin olive oil samples

“…Moreover, AuNPs of different diameter can be produced by various types of synthetic approaches and are easily functionalizable with different molecules (Toma, Zamarion, Toma, & Araki, 2010). AuNPs have been employed in several applications in analytical chemistry field as electrochemical sensors and biosensors (Manjusha, Sureshkumar, & Sandhyarani, 2012;Pingarrón, Yaánez-Sedeño, & González-Cortés, 2008), and in many colorimetric assays (Li, Feng, Zhao, & Tang, 2011;Liu, Yang, Zhao, Liu, & Li, 2013;Vilela, González, & Escarpa, 2012a). In addition, several works exploit the catalytic properties and the large surface area of AuNPs for the quantitative analysis of polyphenolic compounds (Chawla, Rachna, & Pundir, 2011;Li, Li, Xu, & Wei, 2008).…”

One-Step Synthesis of Water-Dispersible and Biocompatible Silicon Nanoparticles for Selective Heparin Sensing and Cell Imaging

“…Heparin is a highly negatively charged linear polysaccharide with a variable length that consists predominantly (>70%) of trisulfated disaccharide repeating units. It has been widely used as a major anticoagulant in various clinical diagnostic and therapeutic processes with about half a billion doses applied annually. − Moreover, heparin plays a vital role in regulating of a range of normal physiological and pathological processes such as venous thromboembolism, inflammation, metabolism, immune defense, cell growth and differentiation, and blood coagulation. − On the contrary, the higher dose and prolonged use of heparin often induce adverse effects, such as thrombocytopenia and hemorrhage or other fatal bleeding complication. ,− Therefore, controlling the amount of heparin during surgery especially for postoperative and long-term care patients in anticoagulant therapy is crucially significant. − However, it is still considered to be a challenge to quantitative measurement of heparin due to its natural polydispersity, chemical heterogeneity, lack of fluorescent properties or significant absorbance, and the interference of analogues. , To date, a lot of methods have made great progress in heparin sensing, such as phosphorescence, spectrophotometry and fluorescence methods, and colorimetric assays. , However, more simple, rapid, and accurate detection of heparin with high sensitivity and selectively is still highly desirable.…”

Heparin sodium-selective ‘on–off’ and lysine-selective ‘off–on’ fluorescence switching of cadmium telluride quantum dots and their analytical applications

“…Therefore, controlling the amount of heparin sodium during surgery especially for postoperative and long-term care patients in anticoagulant therapy is crucially signicant. 13 Recently, a variety of methods have been developed for heparin sodium sensing, such as colorimetric assays 13 spectrophotometry, 14 phosphorescence, 15 and uorescence 16 methods and light scattering technique. 17 To date, gold nanoparticles and cationic polythiophene have been employed to determine heparin sodium by absorption or colorimetric assays.…”