Responsive polymers as smart carriers in tunable catalytic processes

PDMAEMA from α to ω chain ends: tools for elucidating the structure of poly(2-(dimethylamino)ethyl methacrylate)

“…A contribution from both elimination of HBr (mechanism c) and chain transfer (mechanism b) to the formation of populations III and II, respectively, could be additionally present. There are several studies investigating end group analysis of various polymers by mass spectrometry where only ω-hydrogenated chain ends have been detected, 72,79,81,95 hence suggesting the occurrence of chain transfer reactions. In contrast, when populations of ω-unsaturated and ω-hydrogenated chains are detected with equal intensity, disproportionation is the most likely cause.…”

Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery

“…The clear dark-red residue was dissolved in THF and precipitated from MeOH. After isolation and drying in vacuo, a light-beige powder was obtained (82% 9 CH 2 , 9 ′CH 2 ), 2.85−3.03 (m, 6 CH 2 , 6 ′CH 2 , 15 CH 2 , 15 ′CH 2 ), 3.87−4.25 (m, 10 CH, 11 CH 2 , 10 ′CH, 11 ′CH 2 , 16 CH 2 , 16 ′CH 2 ), 5.03− 5.25 (m, 5 CH 2 ), 5.27−5.44 (m, 4 CH 2 ), 7.10−7.19 (m, 13 ′NH), 7.28− 7.41 (m, 13 NH), 7.54−7.89 (m, 2 CH, 3 CH, 14 NH, 14 ′NH), 8.04−8.12 (m, 1 CH).…”

“…Polymers exhibiting a change in the polarity, solubility, or structure as a response to internal or external stimuli, like pH, , temperature, redox conditions, , or light − have been of great interest in recent years. One reason for this interest is the broad field of possible applications of such polymers, which include catalyst immobilization, sensors, , and patterning , as well as tissue engineering, , drug delivery, − and tissue adhesives . Recently, light as a stimulus gained tremendous attention since this trigger can be applied both remotely and accurately by adjusting the parameters of irradiation, such as wavelength, irradiation time, or intensity. , Thus, light-responsive polymers show high potential as efficient and targeted controlled release systems, which reduce side effects compared to conventional therapy. , Photocleavable moieties employed most commonly in such systems are coumarin , and ortho -nitrobenzyl − (oNB) derivatives.…”

“…Polymers exhibiting a change in the polarity, solubility, or structure as a response to internal or external stimuli, like pH, 1,2 temperature, 3 redox conditions, 4,5 or light 6−8 have been of great interest in recent years. One reason for this interest is the broad field of possible applications of such polymers, which include catalyst immobilization, 9 sensors, 10,11 and patterning 12,13 as well as tissue engineering, 14,15 drug delivery, 16−18 and tissue adhesives. 19 Recently, light as a stimulus gained tremendous attention since this trigger can be applied both remotely and accurately by adjusting the parameters of irradiation, such as wavelength, irradiation time, or intensity.…”

“…CH 2 ,8 CH 2 ), 1.49−1.73 (m,9 CH 2 ), 2.91− 3.04 (m,6 CH 2 ), 3.89−4.15 (m,10 CH, 11 CH 2 ), 5.03−5.22 (m, 5 CH 2 ), 5.27−5.44 (m, 4 CH 2 ), 7.28−7.42 (m, 13 NH), 7.58−7.90 (m, 2 CH, , 12 ′CH 3 ), 1.21−1.46 (m, 7 CH 2 , 8 CH 2 , 7 ′CH 2 , 8 ′CH 2 ), 1.47− 1.73 (m, 9 CH 2 , 9 ′CH 2 ), 2.90−3.04 (m, 6 CH 2 , 6 ′CH 2 ), 3.45−3.59 (m, 15 CH 2 , 15 ′CH 2 ), 3.85−4.17 (m, 10 CH, 11 CH 2 , 10 ′CH, 11 ′CH 2 ), 5.04− 5.23 (m, 5 CH 2 ), 5.25−5.44 (m, 4 CH 2 ), 7.09−7.20 (m, 13 ′NH), 7.28− 7.46 (m, 13 NH), 7.54−7.91 (m, 2 CH, 3 CH, 14 NH, 14 ′NH), 8.02−8.13 (m, 1 CH). Polyurethanes 6.…”