Responsiveness and Minimal Clinically Important Differences after Cholecystectomy: GIQLI Versus SF-36

Abstract

The data in this study indicate that clinicians and health researchers should weight disease-specific measures more heavily than generic measures when evaluating treatment outcomes.

Long-term outcomes of laparoscopic cholecystectomy: a prospective piecewise linear regression analysis

“…The GIQLI is recognized as a valid and reliable instrument for measuring HRQoL, especially for patients undergoing cholecystectomy [4][5][6]. Its 36 six items include symptomatology (19 items), emotional impairment (5 items), physical impairment (7 items), social impairment (4 items), and the effects of medical treatment (1 item).…”

“…Studies indicate that LC surgery substantially improves HRQoL [3,4]. Instruments for measuring HRQoL may be disease-specific or generic [5,6]. Disease-specific instruments are administered in longitudinal studies or clinical trials to detect progressive changes after medical or surgical interventions and focus on improvements in symptoms and physical functioning.…”

“…Disease-specific instruments are administered in longitudinal studies or clinical trials to detect progressive changes after medical or surgical interventions and focus on improvements in symptoms and physical functioning. The Gastrointestinal Quality of Life Index (GIQLI) is widely used to assess physical functioning and symptom relief in clinical sites [5,6].…”

“…The ShortForm 36-Item Health Survey (SF-36) is a widely used general health-related instrument that has proved to be useful for outcome assessments [6].…”

Post-cholecystectomy Quality of Life: A Prospective Multicenter Cohort Study of Its Associations with Preoperative Functional Status and Patient Demographics

“…11 We previously analyzed 145 laparoscopic cholecystectomies (LC) and 14 open cholecystectomies (OC) to compare responsiveness and minimal clinically important differences between the gastrointestinal quality of life (GIQLI) and the SF-36. 12 However, in this study, we included more OC procedures and extended our surveys for 6 months. This study therefore examined whether QOL (in individual patients) trends are linear and whether patient demographics and preoperative functional status are longitudinally associated with post-cholecystectomy QOL.…”