Restless Legs Syndrome masquerades as chronic insomnia

Bonakis, Anastasios; Androutsou, Anastasia; Koloutsou, Maria-Evangelia; Vagiakis, Emmanοuil

doi:10.1016/j.sleep.2020.06.003

Cited by 9 publications

(6 citation statements)

References 35 publications

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“…Additionally, the prevalence of RLS in the cohort was 24.2%, which is higher than the 3.0% rate reported in a recent multinational systematic review of 97 studies [32]. It is likely that RLS is also contributing to the high prevalence of insomnia in our cohort, inasmuch as one of the primary consequences of RLS is insomnia [33,34].…”

Section: Discussioncontrasting

confidence: 59%

Exploring Sleep in Caregivers of Children with Autism Spectrum Disorder (ASD) and the Relationship to Health-Related Quality of Life (HRQoL) and Family Quality of Life (FQoL)

Russell,

Baldwin,

Quan

2023

Medicina

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Background and Objectives: To investigate (1) the prevalence of sleep disorder symptoms in caregivers of children with autism spectrum disorder (ASD) and (2) the relationships between caregiver sleep problems and their health-related quality of life and family quality of life. Materials and Methods: Descriptive cross-sectional study of caregivers (N = 62) of children aged 6 to 11 years old diagnosed with ASD and receiving care at a regional autism research and resource center. Results: Participants completed the Sleep Habits Questionnaire (SHQ), the Medical Outcomes Study (MOS) SF-12, and the Beach Center Family Quality of Life Scale (FQoL). Caregivers with longer sleep duration reported better mental health and better family quality of life. Caregivers who reported insomnia symptoms, non-restorative sleep, and insufficient sleep were more likely to report poorer mental health than caregivers who did not report these sleep disorder symptoms. Caregivers with obstructive sleep apnea and restless legs syndrome experienced worse physical quality of life. Conclusions: The physical and mental health of the primary caregiver is essential to the support of the child with ASD and to the functioning of the family. The study findings point to the importance of future research and interventions to enhance sleep health in order to improve quality of life for caregivers of children with ASD.

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Section: Discussioncontrasting

confidence: 59%

Exploring Sleep in Caregivers of Children with Autism Spectrum Disorder (ASD) and the Relationship to Health-Related Quality of Life (HRQoL) and Family Quality of Life (FQoL)

Russell,

Baldwin,

Quan

2023

Medicina

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“…As medidas não farmacológicas podem ser empregadas como terapias complementares, visando a redução da necessidade de doses mais elevadas de tratamentos medicamentosos. Destacam-se entre essas medidas a massagem, o alongamento, a prática de caminhada e a distração cognitiva (como a resolução de quebra-cabeças ou jogos) (Buchfuhrer et al, 2021;Bonakis et al, 2020).…”

Section: Síndrome Das Pernas Inquietas: Bases Fisiopatológicas E Tera...unclassified

Síndrome das Pernas Inquietas: Bases Fisiopatológicas e Terapêuticas

Vytor Cardoso Nobre,

Henrique Costa de Oliveira,

César De Oliveira Cerqueira

et al. 2024

Braz. J. Implantol. Health Sci.

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Introdução: A Síndrome das Pernas Inquietas (SPI), também conhecida como Doença de Willis-Ekbom, é uma desordem neurológica crônica caracterizada por sensações desagradáveis e irresistíveis nas pernas, geralmente durante períodos de repouso ou inatividade, que resultam em um desejo incontrolável de movimentar os membros afetados. Objetivo: Avaliar as bases fisiopatológicas e terapêuticas associadas à síndrome das pernas inquietas. Metodologia: Trata-se de uma revisão bibliográfica que incluiu artigos originais e revisões sistemáticas em inglês e português, que abordaram aspectos fisiopatológicos e manejo da SIP, publicados entre 2014 e 2024, selecionados nas bases de dados PubMed, Scopus e SciELO. Após a seleção criteriosa, foram escolhidos 19 artigos para compor esta revisão bibliográfica. Resultados: O quadro apresenta um padrão fisiopatológico amplo, com diversos aspectos relevantes, incluindo características genéticas, como o padrão dominante e a interação em loci específicos. Além de aspectos ambientais, como a desregulação do sistema dopaminérgico, que corrobora para a sintomatologia do quadro, como também o déficit de ferro periférico e cerebral, sendo considerado um fator biológico-chave na SPI. O manejo da SPI é diverso e envolve intervenções não farmacológicas, como massagem e prática de caminhada, podem complementar a terapia medicamentosa. A escolha do tratamento farmacológico é individualizado e utiliza agonistas dopaminérgicos, ligantes alfa-2-delta, entre outros fármacos. Ademais, outras medidas podem contribuir com a terapêutica do quadro, como a reposição de ferro. Considerações: A SPI é um distúrbio complexo, cuja fisiopatologia ainda não está completamente esclarecida. Dentre os múltiplos fatores, destacam-se a contribuição genética, a deficiência de ferro periférico e cerebral e a desregulação dopaminérgica. O tratamento da SPI envolve intervenções farmacológicas e não farmacológicas. A escolha do tratamento farmacológico é baseada na eficácia em tratar os sintomas primários e as comorbidades associadas.

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“…Restless legs syndrome (RLS), defined as discomfort in lower limbs that induces the need for movement and occurs during the night and during periods of immobility, is found in higher rates among PD patients compared to the general population [48]. RLS in association with periodic limb movements may induce arousal and disrupt normal sleep continuity, contributing to chronic insomnia [48,49]. The clinical diagnosis of RLS is based on the International Restless Legs Syndrome Study Group (IRLSSG) criteria [50].…”

Section: Other Associated Sleep Disordersmentioning

confidence: 99%

Personalized Assessment of Insomnia and Sleep Quality in Patients with Parkinson’s Disease

Diaconu

Falup‐Pecurariu

2022

JPM

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Sleep disturbances are more common in patients with Parkinson’s disease (PD) than in the general population and are considered one of the most troublesome symptoms by these patients. Insomnia represents one of the most common sleep disturbances in PD, and it correlates significantly with poor quality of life. There are several known causes of insomnia in the general population, but the complex manifestations that might be associated with PD may also induce insomnia and impact the quality of sleep. The treatment of insomnia and the strategies needed to improve sleep quality may therefore represent a challenge for the neurologist. A personalized approach to the PD patient with insomnia may help the clinician to identify the factors and comorbidities that should also be considered in order to establish a better individualized therapeutic plan. This review will focus on the main characteristics and correlations of insomnia, the most common risk factors, and the main subjective and objective methods indicated for the assessment of insomnia and sleep quality in order to offer a concise guide containing the main steps needed to approach the PD patient with chronic insomnia in a personalized manner.

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Restless Legs Syndrome masquerades as chronic insomnia

Cited by 9 publications

References 35 publications

Exploring Sleep in Caregivers of Children with Autism Spectrum Disorder (ASD) and the Relationship to Health-Related Quality of Life (HRQoL) and Family Quality of Life (FQoL)

Exploring Sleep in Caregivers of Children with Autism Spectrum Disorder (ASD) and the Relationship to Health-Related Quality of Life (HRQoL) and Family Quality of Life (FQoL)

Síndrome das Pernas Inquietas: Bases Fisiopatológicas e Terapêuticas

Personalized Assessment of Insomnia and Sleep Quality in Patients with Parkinson’s Disease

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