Restoration of Oral Function for Adult Edentulous Patients with Ectodermal Dysplasia: A Prospective Preliminary Clinical Study

Abstract

This study demonstrates that oral function can be restored in edentulous adult ED patients using a comprehensive and systematic treatment protocol involving psychological and oral education, bone augmentation, implant placement, and denture fabrication. Despite these positive outcomes, bone augmentation remains challenging in the anterior region of the maxilla for edentulous adult ED patients.

Anatomical analysis of zygomatic bone in ectodermal dysplasia patients with oligodontia

“…Obvious disadvantages of extensive bone grafting exist, such as donor site morbidity, unpredictable resorption of grafting, staged placement of implant, and prolonged therapy . Zygomatic implant (ZI) was a suitable approach to save treatment time and avoid grafting of the severely atrophic maxilla, with a long‐term survival rate from 95.1% to 100% in ED patients . The bone volume of the zygoma is the key for the placement of the ZI.…”

“…[7][8][9] Zygomatic implant (ZI) was a suitable approach to save treatment time and avoid grafting of the severely atrophic maxilla, with a long-term survival rate from 95.1% to 100% in ED patients. [10][11][12][13][14][15] The bone volume of the zygoma is the key for the placement of the ZI. However, there is no information regarding the evaluation of the characteristics of the zygoma in ED patients.…”

“…Longitudinal tomography showed the measurements of the zygomatic thickness (green line) and length (red line)4 | DISCUSIONFacial bones, such as the maxilla, mandible, alveolar bone, and nasal bone, derived from the ectomesenchyme present abnormalities in ED patients. Additionally, double or quadruple ZIs were used to restore oral function with the advantage of a reduced total treatment time and to avoid complex bone grafting for ED patients with a congenital, edentulous, and severely atrophic maxilla [10][11][12][13][14]. However, it is unclear whether the development of the zygomatic bone and the placement of ZIs are affected in those patients.…”

Complications of Implant Rehabilitation in Ectodermal Dysplasia Patients: A Review Study

“…(3) The two main types of ED are Hidrotic ED (Clouston Syndrome) and Hypohidrotic ED (HED; Christ-Siemens Touraine Syndrome). (4)(5)(6) HED is the most common form of ED with X-linked recessive inheritance. Its incidence is one to seven babies per 10,000 live births.…”

“…Its incidence is one to seven babies per 10,000 live births. (5,7) Hidrotic ED is inherited with an autosomal dominant pattern. (8) Typical appearance characteristics of HED patients comprise sparse hair, wide and prominent forehead and chin, saddle nose, dry skin, skin pigmentation around the eyes and the mouth, vision and hearing problems, periorbital wrinkles, lip thickening, mandibular protrusion, and dished-in midface.…”