2017
DOI: 10.1016/s0140-6736(17)30426-9
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Restoration of vision with ectopic expression of human rod opsin

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Cited by 4 publications
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“…It is thus remarkable that CehajicKapetanovic et al [2] succeeded with this approach. The group used the rd1 mutant mouse as their model.…”
Section: Current Biologymentioning
confidence: 99%
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“…It is thus remarkable that CehajicKapetanovic et al [2] succeeded with this approach. The group used the rd1 mutant mouse as their model.…”
Section: Current Biologymentioning
confidence: 99%
“…While the inner retina remains largely intact, in the absence of outer retinal phototransduction no visual information can be transmitted from the retinal ganglion cells to the brain. In this issue of Current Biology, Cehajic-Kapetanovic and colleagues [2] show that virally mediated gene therapy of human rhodopsin, expressed in the surviving cells of the inner retina, can restore vision-like physiology and behavior to mice blind from outer retinal degeneration.…”
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confidence: 99%