Restricted access supramolecular solvents for the simultaneous extraction and cleanup of ochratoxin A in spices subjected to EU regulation

Caballero-Casero, Noelia; García-Fonseca, Sergio; Rubio, Soledad

doi:10.1016/j.foodcont.2018.01.003

Cited by 25 publications

(8 citation statements)

References 27 publications

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“…Decanoic acid molecules were assembled in SUPRAS as inverted hexagonal aggregates as reported Ruiz et al 22 This carboxylic acid is slightly soluble in water and very soluble in THF, where it forms aggregates via sequential self‐association 23 . The carboxylic groups enclosed the aqueous cavities in this arrangement, and the hydrocarbon chains interacted in a THF microenvironment 24,25 . Similarly, 1‐hexanol produces inverted hexagonal aggregates in THF and coacervates under the addition of water 26 …”

Section: Resultsmentioning

confidence: 81%

“…23 The carboxylic groups enclosed the aqueous cavities in this arrangement, and the hydrocarbon chains interacted in a THF microenvironment. 24,25 Similarly, 1-hexanol produces inverted hexagonal aggregates in THF and coacervates under the addition of water. 26 The SUPRAS produced in this work are expected to extract caffeine efficiently through mixed mode mechanisms.…”

Section: Supras Synthesis and Caffeine Extractionmentioning

confidence: 99%

“…Cooperative and non-covalent interactions between the SUPRAS and caffeine (such as hydrogen bonds between the polar groups of the surfactant and caffeine and polar interactions), as well the high concentration of surfactant in the SUPRAS (e.g., 0.2-0.8 mg μL À1 ) enhances microextraction. 25 In Figure 1, the contour plot for caffeine extraction is presented.…”

Section: Supras Synthesis and Caffeine Extractionmentioning

confidence: 99%

“…decanoic acid or 1-hexanol based SUPRAS as follows: (i) the increase in THF is directly proportional to the THF and water content in SUPRAS, and inversely proportional to the decanoic acid or 1-hexanol content 25,26 ; (ii) increasing the 1-hexanol or decanoic acid concentration, increases its incorporation into SUPRAS and the amount of water, as a consequence the THF amount decrease. 26 In SUPRAS produced with 5% of decanoic acid or 1-hexanol and 10% of THF, the water content was 6% and 3.5% respectively, and the THF percentage was 26% and 31.5%.…”

Section: Supras Synthesis and Caffeine Extractionmentioning

confidence: 99%

“…26 In SUPRAS produced with 5% of decanoic acid or 1-hexanol and 10% of THF, the water content was 6% and 3.5% respectively, and the THF percentage was 26% and 31.5%. 25,26 This could be caused by a difference in solubility. The amphiphile-amphiphile interactions could be greater than amphiphile-solvent interactions in decanoic acid-based SUPRAS.…”

Section: Supras Synthesis and Caffeine Extractionmentioning

confidence: 99%

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Tuneable solvents‐based extraction for the recovery of caffeine from coffee wastewater

José Luis,

Carlos,

Laura Sofía

2023

Env Prog and Sustain Energy

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Tunable solvents represent a new generation of environmentally friendly solvents with potential applications in the effective extraction of bioactive compounds, including supramolecular solvents (SUPRAS). This study aimed to optimize caffeine extraction from coffee processing wastewater (CWW) using SUPRAS of various compositions. An extreme vertices design was employed to evaluate the SUPRAS composition. The synthesis of SUPRAS involved two amphiphiles (1‐hexanol and decanoic acid) in hydro‐organic solutions of tetrahydrofuran (THF). A statistical modeling approach was used to characterize the process and determine the optimal conditions for potential scale‐up within the coffee processing industry. The results indicated that SUPRAS offer a promising alternative to traditional solvents for extracting caffeine from CWW. The highest experimental extraction rate (~ 62%) was achieved using a 15% 1‐hexanol in a hydro‐organic solution of THF (47% v/v). This mixture corresponded to the optimum predicted by a special cubic statistical model (R2 = 0.9367; Adj‐R2 = 0.8608, and RSME = 3.2795). The percentage of caffeine extracted from CWW is considered acceptable, given the compound's affinity for water and the rapid (1 min) and straightforward approach employed. Moreover, the use of SUPRAS reduced solvent consumption, and the proposed statistical model identified conditions that maximized caffeine extraction while minimizing THF usage. This method can potentially lower process costs and solvent consumption. For large‐scale extraction, centrifugation can be substituted with spontaneous sedimentation. Overall, these findings have significant implications for the valorization of CWW, providing a sustainable and efficient method for the extraction of valuable compounds.

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