Results of cesium needle interstitial implantation for carcinoma of the oral tongue

Hareyama, Masato; Nishio, Makoto; Saitô, Akio; Kagami, Yoshikazu; Asano, Katsushi; Oouchi, Atsushi; Narimatsu, N; Somekawa, Yukihiro; Sanbe, Shigeo; Morita, Kazuo

doi:10.1016/0360-3016(93)90141-h

Cited by 40 publications

(14 citation statements)

References 10 publications

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“…Overall 5‐year survival (OS and DSS) has been reported as between 37% 2–5 and 85%. 6 Significant survival differences by stage grouping have been reported by Gujrathi et al 5 for multiple treatment modalities (5‐y OS for stages I [64%], II [46%], III [42%], and IV [16%] [ P = .001]); by Hareyama et al 7 for two forms of RT (5‐y OS for stages I [85%], II [69%], III [65%], and IV [40%] [ P = .05]); and by Hicks et al 6 for surgery alone (5‐y DSS for stages I [89%], II [95%], III [76%], and IV [65%] [ P = .05]). Reports comparing specific treatment modalities have failed to show a significant survival difference.…”

Section: Discussionmentioning

confidence: 94%

Analysis of Treatment Results for Oral Tongue Cancer

et al. 2002

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Significant improvement in DSS was seen in patients with clear margins, early stage grouping and clinical (pretreatment) tumor stage, and negative nodes. Significant decrease in DSS was seen in patients with close or involved margins, advanced stage grouping and clinical (pretreatment) tumor staging, positive clinical (pretreatment) node staging, and tumor recurrence. Obtaining clear margins of resection is crucial because it significantly affects survival. A minimum of 5 years of close monitoring is recommended because of the high incidence of second primary cancers.

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Section: Discussionmentioning

confidence: 94%

Analysis of Treatment Results for Oral Tongue Cancer

et al. 2002

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“…Since our cases were nearly T3 in terms of tumor thickness, in the sense that they needed two-plane implantation, our treatment results are comparable with theirs. The aforementioned study indicates that the overall incidence of ulceration of the tongue and mandibular complication was 20% (26/130) and 13% (17/130), respectively 13. Although the follow-up period is still short, our patients did not show any signs of complications in soft tissues and mandibles.…”

Section: Discussionmentioning

confidence: 51%

“…The high local control rate in this study might have been achieved because of the careful treatment planning based on these images. As to the local control rate, Hareyama, et al13 reported treatment results of 130 patients treated with brachytherapy. Their local control rate for T3 cases was 70.9% 13.…”

Section: Discussionmentioning

confidence: 99%

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Cesium Implant for Tongue Carcinoma with a Thickness of 1.5 cm or More: Cases Successfully Treated with a Modified Manchester System

et al. 2010

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PurposeDeciding on treatment carcinoma of the tongue when the tumor has a thickness of 1.5 cm or more is difficult. Surgery often requires wide resection and re-construction, leading to considerable functional impairment. A cesium implant is an attractive option, but according to the Manchester System, a two plane implant is needed.Materials and MethodsAccording to the textbook, a tumor is sandwiched between the needles, which are implanted at the edge of the tumor. This may cause an unnecessarily high dose to the outer surface of the tongue, which sometimes leads to a persistent ulcer. To avoid this complication, we invented a modified implantation method, and applied the method to five consecutive patients.ResultsWith a minimum follow-up of 2 years, all primary tumors in 5 consecutive patients have been controlled. No complications occurred in soft tissue of the tongue or in the mandible.ConclusionOur modified Manchester System was feasible and effective for tumors that has a thickness of 1.5 cm or more.

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“…Low-dose-rate (LDR) and high-dose-rate (HDR) interstitial brachytherapy (ISBT), with or without external beam radiotherapy (EBRT), shows a high rate of local control that is nearly equivalent to that of radical surgery [1, 2, 3, 4, 5, 6, 7, 8, 9, 10]. We also showed that local control rates using HDR-ISBT for early mobile tongue cancer is an effective alternative treatment [7, 8].…”

Section: Purposementioning

confidence: 99%

Edema worsens target coverage in high-dose-rate interstitial brachytherapy of mobile tongue cancer: a report of two cases

Yoshida¹,

Yamazaki²,

Kotsuma³

et al. 2017

jcb

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PurposeWe report our study on two patients to highlight the risk of underdosage of the clinical target volume (CTV) due to edema during high-dose-rate interstitial brachytherapy (HDR-ISBT) of mobile tongue cancer.Material and methodsTo treat the lateral side of the CTV, flexible applicator tubes were implanted on the mouth floor. Two-dimensional planning was performed using X-ray images for Case 1, and three-dimensional (3D) planning was performed using computed tomography (CT) for Case 2. Prescribed doses for both cases were 54 Gy in nine fractions.Case reportsCase 1 was treated for cancer of the right lateral border of the tongue in 2005. Tongue edema occurred after implantation, and part of the lateral border of the tongue protruded between the applicator tubes. Acute mucosal reaction abated in the protruded area earlier than in the other parts of the CTV. In this case, the tumor recurred in this area 5 months after the treatment. Case 2 was treated for cancer of the left lateral border of the tongue. Because tongue edema occurred in this case also, plastic splints were inserted between the applicator tubes to push the edematous region into the irradiated area. The mucosal surface of the CTV was covered by the 70% isodose, and 100% isodose line for before and after splint insertion. Local control of the tumor was achieved 4 years after treatment.Discussion and conclusionsTo ensure sufficient target coverage, 3D image-based planning using CT should be performed, followed by re-planning using repeated CT as needed. Also, the development of devices to prevent protrusion of the edematous tissue outside the target area will help to ensure the full dosing of CTV.

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Results of cesium needle interstitial implantation for carcinoma of the oral tongue

Cited by 40 publications

References 10 publications

Analysis of Treatment Results for Oral Tongue Cancer

Analysis of Treatment Results for Oral Tongue Cancer

Cesium Implant for Tongue Carcinoma with a Thickness of 1.5 cm or More: Cases Successfully Treated with a Modified Manchester System

Edema worsens target coverage in high-dose-rate interstitial brachytherapy of mobile tongue cancer: a report of two cases

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