Results of salvage surgery following radical radiotheraphy for laryngeal carcinoma

Shamboul, K.; Doyle-Kelly, W.; Bailey, David P.

doi:10.1017/s0022215100147681

Cited by 20 publications

(13 citation statements)

References 10 publications

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“…Viani et al 16 also reported that many patients with laryngeal recurrence after failed RT had an advanced tumor by the time of the diagnosis, with almost half being transglottic T3 or T4 tumors. Therefore total laryngectomy remains the most frequently performed salvage procedure for RT failure 10,11,16‐18 …”

Section: Introductionmentioning

confidence: 99%

Supracricoid Partial Laryngectomy After Failed Laryngeal Radiation Therapy

Laccourreye¹,

Weinstein²,

Naudo³

et al. 1996

The Laryngoscope

132

134

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Twelve patients managed with supracricoid partial laryngectomies (SCPLs) after failed laryngeal radiation therapy (RT) were evaluated. None of the recurrent tumors were amenable to vertical or horizontal partial laryngectomy. Results were analyzed for tracheostomy decannulation, oral alimentation, morbidity, local control, and survival. Major complications included perichondritis (2 patients), laryngeal stenosis (2 patients), and pneumonia from aspiration (1 patient). Mucocutaneous fistula and cricoarytenoid joint ankylosis were not encountered. Margins of resection were uninvolved in all cases. The Kaplan-Meier 3-year actuarial survival and local control estimate was 83.3%. Salvage total laryngectomy allowed for an overall 100% local control rate and a 75% laryngeal preservation rate. This preliminary report suggests that, in patients with failed laryngeal RT not amenable to vertical or horizontal partial laryngectomy, the SCPL procedures should be discussed before advocating salvage total laryngectomy. Further series analyzing the role and limitations of the various SCPL procedures after failed laryngeal RT are warranted.

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Section: Introductionmentioning

confidence: 99%

Supracricoid Partial Laryngectomy After Failed Laryngeal Radiation Therapy

Laccourreye¹,

Weinstein²,

Naudo³

et al. 1996

The Laryngoscope

132

134

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“…To avoid total laryngectomy as much as possible, organ-preservation chemoradiation protocols and conservative surgery have been used for primary treatment of laryngeal cancer, reserving total laryngectomy as salvage treatment. [1][2][3] Local recurrence rate after radiation therapy (RT) ranges from 5% to 13% for T1 and from 25% to 30% for T2 laryngeal cancer.4,5 Surgical management of recurrences after RT failure encompasses endoscopic laser excision, 6-8 partial laryngectomies through an open-neck approach, 4,[9][10][11][12][13] and total laryngectomy, which still remains the most widely used procedure in such a scenario. …”

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confidence: 99%

Supracricoid partial laryngectomies after radiation failure: A multi‐institutional series

Pellini¹,

Pichi²,

Ruscito³

et al. 2007

Head & Neck

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“…Until 1991, 6 206 cases of partial laryngectomy after failure to RT were reported in the English literature, and most patients required loss of the larynx to achieve a cure after a radiation failure. 2,3,[9][10][11] To evaluate time of recurrence and locoregional control with partial or total laryngectomy after failure to RT for T1-T2 squamous cell laryngeal carcinoma, we retrospectively reviewed 29 patients treated with RT who recurred between 1981 and 1996.…”

mentioning

confidence: 99%