Results With Titanium Ossicular Reconstruction Prostheses

Gardner, Edward K.; Jackson, C. Gary; Kaylie, David M.

doi:10.1097/00005537-200401000-00011

Cited by 97 publications

(107 citation statements)

References 19 publications

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“…Extrusion rates in our study were comparable to those of Ho et al [13] (4%) and of Begall et al [10] (4.4%). Rates of revision surgery were higher compared to other studies by Stupp et al [11] (5.6%), Martin and Harner [15] (7%) and Gardner et al [14] (6%).…”

Section: Discussioncontrasting

confidence: 59%

“…A study done by Stupp et al [11,12] found a success rate of 76%, studies by Ho et al [13] and Gardner et al [14] have reported success rate of 56% (64% for PORP and 45% for TORP) and 71% for PORP and 44% for TORP respectively. In the present study success was considered after attaining dry ear and with a postoperative improvement of an Air Bone Gap of 20 dB or less and our success rate was 76.47% (75% for PORP and 77.77% for TORP).…”

Section: Discussionmentioning

confidence: 96%

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Preliminary Hearing Results of Tympanomastoidectomies Using Titanium Prostheses: Scenario in a Developing Country

Sayal¹,

Taneja²,

Gulati³

2013

IJOHNS

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The study was done to review postoperative hearing gain of patients with different Middle Ear Risk Index (MERI) undergoing Tympanomastoidectomies with titanium prostheses reconstruction. A Retrospective chart review was performed from September 2009 to December 2011. Of the 17 cases, 9 had moderate MERI while 8 had severe MERI. 9 patients underwent Tympanomastoidectomy with Total Ossicular Reconstruction Prostheses (TORP) and 8 with Partial Ossicular Reconstruction Prostheses (PORP). Hearing gain of 25.31 dB was achieved in cases with moderate MERI compared to 29.37 dB in severe MERI. Less than 20 dB average air-bone gap was achieved in 75% of PORP and 77.77% of TORP reconstructions. In developing countries with limited resources, decision regarding ossicular reconstruction should be made taking into account MERI, intra operative findings and type of surgery. Best results are achieved in cases of CWD with TORP and ICW with PORP.

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Section: Discussioncontrasting

confidence: 59%

Section: Discussionmentioning

confidence: 96%

Preliminary Hearing Results of Tympanomastoidectomies Using Titanium Prostheses: Scenario in a Developing Country

Sayal¹,

Taneja²,

Gulati³

2013

IJOHNS

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“…One or all of these factors can have implications in the use of ossicular prostheses, extrusions and middle ear sound conduction. Similar hearing outcomes have been observed in other studies on type 3 ossicular reconstruction using titanium prostheses [16,20,21].…”

Section: Comparison With Other Studiessupporting

confidence: 89%

Cartilage Palisades in Type 3 Tympanoplasty: Functional and Hearing Results

Vashishth

Mathur

Verma

2013

Otolaryngol.--head neck surg.

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To evaluate the functional and hearing outcomes using full thickness broad cartilage palisades for tympanic membrane reconstruction in type 3 tympanoplasty with titanium prostheses. The retrospective study performed at a tertiary referral institute included 30 patients with posterior mesotympanic retraction pockets or tympanic membrane perforations requiring tympanic membrane and type 3 ossicular reconstruction. Patients with disease extending beyond the aditus requiring canal wall down mastoidectomy were excluded. Disease removal from posterior mesotympanic and epitympanic recesses was confirmed using angled endoscopy and ossicular reconstruction was performed using titanium partial or total ossicular replacement prostheses. Tympanic membrane reconstruction was done, with or without attic reconstruction, using full thickness broad cartilage palisades harvested from the tragus with perichondrium attached laterally. Patients were assessed at 24 and 48 weeks for graft status and any evidence of implant extrusion. Hearing evaluation was done using subjective assessment and pure tone audiometry. In total, 27 out of 30 patients had intact and completely healed grafts at 48 weeks postoperatively (a success rate of 90 %) showing full union and epithelialization of palisades, and with three patients displaying small defects. The mean pure tone air bone gap pre-and postoperatively was 32.4 and 8.8 dB, respectively, with most patients reporting satisfactory postoperative hearing. No evidence of implant extrusion was found in the 48-week period. Tympanic membrane reconstruction using full thickness palisades of tragal cartilage provides good functional and hearing outcomes in type 3 tympanoplasty with titanium prostheses.

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“…Nowadays, in some ear specialists' opinion, long-term follow-ups may even reach up to 20% of extrusion-related failures. Recently, both hydroxylapatite (HA), due to its chemical similarity to the mineral phase of the osseous tissue (Grote et al 1981;Grote 1986;Wehrs 1995;Goldenberg and Driver 2000;Rondini-Gilli et al 2003) and, more recently, titanium (Ti) (Stupp et al 1999;Zenner et al 2001;Ho et al 2003;Gardner et al 2004;Martin and Harner 2004), due to its processability in minute shape and its success as bone substitute, are the most commonly used biomaterials for ossicular prostheses.…”

Section: Introductionmentioning

confidence: 99%

Novel biological/biohybrid prostheses for the ossicular chain: fabrication feasibility and preliminary functional characterization

Danti

Stefanini

D’Alessandro

et al. 2009

Biomed Microdevices

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Alternatives for ossicular replacements were fabricated in order to overcome persisting rejections in middle ear prosthetization. Unlike the synthetic prostheses in fashion, we propose biological and biohybrid replacements containing extra cellular matrix (ECM) molecules to improve biointegration. In this study, ECM-containing devices shaped as Partial Ossicular Replacement Prostheses (PORPs) were fabricated reproducing the current synthetic models. Biological PORPs were obtained from human decellularized cortical bone allografts by computer numerically controlled ultraprecision micromilling. Moreover, porous PORP-like scaffolds were produced and cultured with osteoinduced human mesenchymal stromal cells to generate in vitro bone ECM within the scaffold porosity (biohybrid PORPs). The acoustic responses of such devices were investigated and compared to those of commercial prostheses. Results showed that biological PORPs transmit mechanical signals with appropriate frequencies, amplitudes, and with early extinction time. Although signal transmission in biohybrid PORPs showed insufficient amplitude, we believe that tissue engineered constructs represent the new challenge in ossiculoplasty.

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Results With Titanium Ossicular Reconstruction Prostheses

Abstract: Newer titanium-based ossicular reconstruction devices represent an improvement over previously used non-titanium-based prostheses. The authors think that this improvement is realized rapidly because no learning curve existed in their data.

Cited by 97 publications

References 19 publications

Preliminary Hearing Results of Tympanomastoidectomies Using Titanium Prostheses: Scenario in a Developing Country

Preliminary Hearing Results of Tympanomastoidectomies Using Titanium Prostheses: Scenario in a Developing Country

Cartilage Palisades in Type 3 Tympanoplasty: Functional and Hearing Results

Novel biological/biohybrid prostheses for the ossicular chain: fabrication feasibility and preliminary functional characterization

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