Resuscitation Fluids for the Treatment of Hemorrhagic Shock in Dogs: The Effects on Myocardial Blood Flow

Impact of Different Clinical Perfusates During Normothermic Ex Situ Liver Perfusion on Pig Liver Transplant Outcomes in a DCD Model

“…It has an important effect on increasing intravascular volume and oxygen delivery but also at decreasing clot formation. 14-17 On the other side, Steen solution has physiologic levels of Na + , Cl − , and K + . It also contains human albumin and dextran (D)-40, both characterized for expanding the intravascular volume.…”

Fluid Resuscitation

“…Although the colloid-treated patients in this study experienced less pulmonary edema than NS controls (20), other clinical studies did not show a difference in pulmonary effects between colloids and crystalloids (21, 22). Other reported benefits of colloid versus crystalloid solutions in animal models were more rapid restoration of tissue perfusion (23, 24), improved oxygen delivery (23, 24), reduced gut injury (25), and reduced lung injury (26); however, they did not result in meaningful reduction in mortality for trauma patients according to a critical analysis of a number of meta-analyses of human studies comparing colloid to crystalloid (27). Furthermore, 2 meta-analyses suggested that colloids were associated with an increased mortality in trauma patients (28, 29).…”