Retention models for programmed gas chromatography

Rapid Temperature-Programmed Separation and Retention Prediction on a Novel Packed-Capillary Column in Gas Chromatography

“…Downsizing of the packed column also permits the use of the resulting miniaturized packed column in a modern capillary GC system without any special modification to the instruments, although the compatibility of the packed column to the temperature-programmed operation should be considered as typically reported in several publications dealing with the theoretical prediction of the retention time for separation with temperature programming. [13][14][15][16][17][18][19][20][21] In contrast to a number of papers for a theoretical prediction of the retention in GC, a comprehensive comparison of the compatibility of packed columns having different internal diameters to a rapid temperature program in a modern GC system had been quite limited. [21][22][23] In this work, novel packed-capillary columns were developed with a thin-wall capillary of stainless-steel, and the compatibility to a fast temperature-programmed separation was studied on the basis of a theoretical prediction of the retention by a numerical-integration method.…”

“…[13][14][15][16][17][18][19][20][21] In contrast to a number of papers for a theoretical prediction of the retention in GC, a comprehensive comparison of the compatibility of packed columns having different internal diameters to a rapid temperature program in a modern GC system had been quite limited. [21][22][23] In this work, novel packed-capillary columns were developed with a thin-wall capillary of stainless-steel, and the compatibility to a fast temperature-programmed separation was studied on the basis of a theoretical prediction of the retention by a numerical-integration method. To confirm the compatibility of the developed packed-capillary columns to the temperature program, the observed retention data of a standard sample at different temperature-programming ramps were compared with the corresponding theoretical value predicted by a set of retention data at each column temperature.…”

Fast and accurate numerical method for predicting gas chromatography retention time

“…6in terms of is possible when the temperature is kept constant [2,19,22], otherwise numerical methods need to be applied to obtain its value [1,23,26].…”

“…The estimation of these parameters can be obtained under the isothermal conditions of the chromatographic column, and such estimate presents an analytical solution. However the same does not occur if temperature ramps are applied, which would require solving the problem with the use of numerical methods [1].…”

“…According to [1][2][3], the use of temperature ramps when estimating parameters produces better results in terms of t r prediction than in case of parameters obtained in constant conditions. However, the first problem results in a non-linear regression, and an elevated number of evaluations of t r can be required until its convergence.…”