Due to the risk of fetal anomaly, pregnant women of advanced maternal age are given the option to undergo amniocentesis. This study aimed to describe couples' decision-making process regarding amniocentesis, and assess whether it is influenced by marital intimacy and men's attendance of genetic counseling. During pregnancy, 112 couples answered the Personal Assessment of Intimacy in Relationships questionnaire and scales regarding the decision to undergo amniocentesis. Most couples shared and reached an agreement regarding this decision. Higher levels of marital engagement and communication, but not men's attendance, were associated with higher agreement, influence, and decision sharing. Clinical implications are discussed.