Retiform purpura: A diagnostic approach

Early cutis marmorata telangiectatica congenita masquerading as ulcerated retiform purpura: a diagnostic trap

“…However, early morphology may be atypical, lacking the classic pattern of CMTC 3 . This was the case with our patient whose initial lesion had features most consistent with retiform purpura, including peripheral branching at the margins and an ulcerated purpuric center 4 . These findings were suggestive of an underlying vasculopathy or vasculitis; however, our group was able to defer an unnecessary workup based on prior experience with similar clinical presentations of CMTC.…”

“…This finding may support the diagnosis of CMTC. However, when skin lesions appear as ulcerated purpura as in this case, the differential diagnosis should include pathological processes related to vessel wall damage or vessel lumen occlusion 4 . Such processes include infections and thromboembolic disorders.…”

“…Such processes include infections and thromboembolic disorders. Accordingly, a more extensive workup with skin biopsy may be warranted to rule out neonatal vasculopathy in cases where reversible or life‐threatening causes are suspected including sepsis, prothrombotic disorders, or perinatal injury 4,5 …”

Glomeruloid reactive angioendotheliomatosis in a woman with systemic lupus erythematosus and antiphospholipid syndrome mimicking reticular erythematous mucinosis

“…1,9 While histology was very specific, the clinical presentation in our patient was rather peculiar, and we considered the differential diagnosis of REM, acute cutaneous lupus erythematosus, and retiform purpura. [10][11][12][13] REM was plausible, typically affecting the midline of the chest or the upper portion of the back of young and middle-aged women. However, intravascular proliferation is not a histopathology finding in REM, showing a perivascular and periappendageal, predominantly lymphocytic infiltrate with dilated capillaries in the superficial and deep dermis.…”

Acute retiform purpura caused byMorganella morganii

“…Retiform purpura is a specific sign within the spectrum of reticulate eruptions of vascular origin. This damage can occur either by vessel wall compromise (vasculitis, angioinvasive micro-organism, depositional disease) or by vessel lumen occlusion (thrombotic or embolic disease) 1…”