Retinal Angiomatous Proliferation in Age–related Macular Degeneration

Abstract

Retinal angiomatous proliferation appears to be a distinct subgroup of neovascular ARMD. It may present in one of three vasogenic stages: IRN, SRN, or CNV. Whereas ICG angiography is helpful in diagnosing RAP and in documenting the stage of the neovascularized process, it is frequently difficult to determine the precise nature and location of the new vessel formation. It is important for clinicians to recognize the vasogenic potential and the associated manifestations of this peculiar form of neovascular ARMD so that a proper diagnosis can be made, and when possible, an appropriate management administered.

Telangiectasias perimaculares idiopáticas

“…É um processo de proliferação vascular intrarretiniana, semelhante ao RAP (Retinal Angiomatous Proliferation) (5,6) . Nessa fase, a despeito da proliferação vascular, o EPR mantém-se intacto (Figura 6).…”

Clinical Characteristics and Current Treatment of Age-Related Macular Degeneration

“…Other names for this entity include "retinal angiomatous lesion," "deep retinal vascular anomalous complex," "retinal anastomosis to the lesion," "retinal vascular anomalous complex," "retinal choroidal anastomosis," and "type III neovascularization" (Yannuzzi et al 2001;Freund et al 2008). As the multiple names suggest, there is much debate over its pathogenesis and natural history.…”

Imaging retinochoroidal anastomosis via spectral-domain optical coherence tomography

“…Such an anastomoses can result from RAP or disciform scar formation. 1,3,4 Identification of such an anastomoses by SD-OCT may guide treatment.…”

“…This is a subgroup of neovascular AMD (Figure 1a-d). 1 Serial SD-OCT B-scans revealed a pigment epithelial detachment (PED) with intra-retinal fluid and a high-reflective lesion in the inner retina corresponding to the intra-retinal hemorrhage seen on color photography OD (Figure 1e). 2 After 18 months and seven intravitreal ranibizumab injections, the BCVA was 20/240 OD.…”