Retinal autofluorescence imaging in patients with pseudoxanthoma elasticum

Morillo, M.J.; Mora, Jaume; Soler, A.; García-Campos, J.M.; García-Fernández, María; Sánchez, Pablo; Valdivieso, P.

doi:10.1016/s2173-5794(11)70003-2

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2017

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“…This process usually occurs at the third or fourth decade of life [1]. Histopathology demonstrates calcium deposition in the Bruch's membrane which has several well demarcated breaks [12].…”

Section: Discussionmentioning

confidence: 99%

Angioid Streaks in Psuedoxanthoma Elasticum

Mohammadpour¹,

Ebrahimiadib²,

Tabatabaei³

et al. 2017

OJOph

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Pseudoxanthoma elasticum (PXE) is a hereditary disorder that affects primarily the elastic tissues of skin, eyes and blood vessels. Its estimated prevalence is thought to be 1:25,000 -100,000. PXE patients also carry an increased risk for cardiovascular and gastrointestinal diseases. Early diagnosis can play a crucial role in preventing early loss of vision and systemic complications in these patients however despite having characteristic clinical features; it is still to a large extent being under-diagnosed. Here we present two cases of PXE with reduced vision.

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Section: Discussionmentioning

confidence: 99%