Retinal contour modelling to reproduce two-dimensional peripheral spherical equivalent refraction

Li, Qing

doi:10.1364/boe.426413

Cited by 5 publications

(2 citation statements)

References 41 publications

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“…A rapidly growing research revealed that the onset and progression of myopia should be a complex and multifactorial process. One of the current hypotheses is peripheral defocus theory [36][37][38] , which have been shown in animal studies that peripheral myopic defocus could modulate not only peripheral ocular growth, but also axial growth [39] . However, recent investigations in humans have failed to find the correlation between peripheral refraction and myopia progression [40] .…”

Section: Resultsmentioning

confidence: 99%

Photopic pupil size change in myopic orthokeratology and its influence on axial length elongation

Zhu¹,

Du²,

He³

et al. 2022

Int J Ophthalmol

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AIM: To explore the photopic pupil size behavior in myopic children undergoing overnight orthokeratology (ortho-k) over 1-year period and its effects on the axial elongation. METHODS: A total of 202 Chinese myopic children were enrolled in this prospective clinical trial. Ninety-five subjects in ortho-k group and eighty-eight subjects in spectacle group completed the 1-year study. Axial length (AL) was measured before enrollment and every 6mo after the start of ortho-k. The photopic pupil diameter (PPD) was determined using the Pentacam AXL and measured in an examination room with lighting of 300-310 Lx. Stepwise multiple linear regression analysis was used to identify variables contribution to axial elongation. RESULTS: Compared with spectacle group, the average 1-year axial elongation was significantly slower in the ortho-k group (0.25±0.27 vs 0.44±0.23 mm, P<0.0001). In ortho-k group, PPDs significantly decreased from 4.21±0.62 mm to 3.94±0.53 mm after 1mo of lens wear (P=0.001, Bonferroni correction) and the change lasts for 3-month visit. No significantly change during the other follow-up visits was found (P>0.05, Bonferroni correction). The 4.81 mm PPD may be a possible cutoff point in the ortho-k group. Subjects with PPD below or equal to 4.81 mm tended to have smaller axial elongation compared to subjects with PPD above 4.81 mm after 1-year period (t=-3.09, P=0.003). In ortho-k group, univariate analyses indicated that those with older age, greater degree of myopia, longer AL, smaller baseline PPD (PPDbaseline) experienced a smaller change in AL. In multivariate analyses, older age, greater AL and smaller PPDbaseline were associated with smaller increases in AL. In spectacle group, PPD tended to be stable (P>0.05, Bonferroni correction) and did not affect axial growth. CONCLUSION: PPDs experience significantly decreases at 1-month and 3-month ortho-k treatment. Children with smaller PPD tend to experience slower axial elongation and may benefit more from ortho-k.

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Section: Resultsmentioning

confidence: 99%

Photopic pupil size change in myopic orthokeratology and its influence on axial length elongation

Zhu¹,

Du²,

He³

et al. 2022

Int J Ophthalmol

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“…These findings indicate that the chief rays on both sides of the lens model are almost collinear to each other-having the feature of the optical axis defined in the paraxial optics. In the paraxial optical theory, the wavefront vergence at two conjugated points on the optical axis are always linear to each other [24], which could partially explain the linear relationship between Φ pupil−SE and v in−SE .…”

Section: Discussionmentioning

confidence: 99%

Impacts of the gradient-index crystalline lens structure on its peripheral optical power profile

2022

Advanced Optical Technologies

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The crystalline lens makes an important contribution to the peripheral refraction of the human eye, which may affect the development and progression of myopia. However, little has been known about the peripheral optical features of the crystalline lens and its impacts on the peripheral ocular refraction. This study aims to investigate the relationship between the structural parameters of the crystalline lens and its peripheral power profile over a wide visual field. The peripheral power profile is defined with respect to the entrance and exit pupil centers along the chief rays. Analysis is performed by three-dimensional ray tracing through the gradient refractive index (GRIN) lens models built from measurement data. It has been found that the vergence of the wavefronts at the entrance and the exit pupil centers of the lens show an approximate linear correlation to each other for each field angle. The exponent parameters of the axial refractive index profile and the axial curvature profile, and the asphericity of the posterior lens surface are found to be the most influential parameters in the peripheral power profiles. The study also shows that there can be significantly different, sometimes unrealistic, power profiles in the homogeneous lens model compared with its corresponding GRIN model with the same external geometry. The theoretical findings on the peripheral lens properties provide a new perspective for both wide-field eye modelling and the design of intraocular lenses to achieve normal peripheral vision.

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Optical and retinal changes influenced by different lighting conditions

Orduna-Hospital,

Sanchez-Bautista,

Fernández-Espinosa

et al. 2024

Experimental Eye Research

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Retinal contour modelling to reproduce two-dimensional peripheral spherical equivalent refraction

Cited by 5 publications

References 41 publications

Photopic pupil size change in myopic orthokeratology and its influence on axial length elongation

Photopic pupil size change in myopic orthokeratology and its influence on axial length elongation

Impacts of the gradient-index crystalline lens structure on its peripheral optical power profile

Optical and retinal changes influenced by different lighting conditions

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