Retinal detachments after Boston Keratoprosthesis: incidence, predisposing factors, and visual outcomes

Jardeleza, Maria Stephanie R; Rheaume, Marc Andre; Chodosh, James; Lane, Anne Marie; Dohlman, Claes H.

doi:10.5693/djo.01.2015.10.001

Cited by 21 publications

(15 citation statements)

References 22 publications

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“…Retinal detachment was observed in two patients of the present study. Patients with underlying autoimmune systemic disorders should be closely monitored for the development of retinal detachment following KPro surgery (33). In the present study, corneal melting occurred in two patients (10%), the rate of which was decreased compared with that reported by Cade et al (34).…”

Section: Discussionsupporting

confidence: 40%

Post‑operative outcomes associated with Boston type 1 keratoprosthesis implantation in Northeast China

et al. 2018

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The aim of the present study was to investigate the post-operative outcomes associated with Boston type 1 keratoprosthesis (Kpro-1) implantation in the treatment of patients with corneal blindness in Northeast China. Clinical data of patients who had undergone Kpro-1 implantation between July 2010 and November 2014 were retrospectively collected. The visual performance, implant retention and post-surgical complications were recorded for each patient. A total of 20 patients (20 eyes) with corneal blindness were included in the study. Prior to surgery, the patients exhibited poor vision and decreased levels of light perception. At 3 days, 1 month, 6 months, 1 year and 2 years post-surgery, logarithm of the minimum angle of resolution values were significantly decreased compared with the pre-operative values. The initial Kpro-1 implants were retained in 16 eyes. Regarding the post-operative complications, six patients exhibited retroprosthetic membrane formation, two patients presented with endophthalmitis, two patients developed secondary glaucoma, two patients experienced optical cylinder detachment, two patients presented with corneal melting, three patients had retinal detachment, three patients developed corneal ulcers and one patient had secondary optic neuropathy. Overall, the results of the present study suggested that implantation with Kpro-1 may represent an alternative therapeutic strategy for patients following previously failed keratoplasty in Northeast China. Serious complications associated with Kpro-1 implantation are common, and thus, suitable patient selection, continuous follow-up and early treatment interventions are recommended.

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Section: Discussionsupporting

confidence: 40%

Post‑operative outcomes associated with Boston type 1 keratoprosthesis implantation in Northeast China

et al. 2018

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“…Such a situation is likely to get worse with every subsequent surgical procedure, including a B-KPro. It can result in RPM, vitreous opacities, cystoid macular edema, epiretinal membrane, or-worst of all-a retinal detachment, which has a poor record of repair [40,46,65]. Again, autoimmune disease is the leading risk factor.…”

Section: Infections Prophylaxismentioning

confidence: 96%

The Boston keratoprosthesis 2014: a step in the evolution of artificial corneas

Dohlman

Cruzat

White

2014

Spektrum Augenheilkd.

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“…21 Vitreous inflammation can lead to posterior vitreous detachment with subsequent retinal breaks, and idiopathic vitritis is a reported risk factor for RD after KPro. 4,21,22 Idiopathic vitritis occurred frequently in our series, but detailed risk factor analysis was not performed because of the small cohort size and is reported elsewhere. 4 It has also been shown that a chronic low grade of inflammation from the KPro device itself can promote a strong inflammatory response within the retina, leading to an aggressive PVR response following RD.…”

Section: Discussionmentioning

confidence: 99%