Retinitis pigmentosa in Benin, Nigeria

Ukponmwan, CU; Atamah, A

doi:10.4314/eamj.v81i5.9169

Cited by 13 publications

(34 citation statements)

References 13 publications

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“…The mean age of 39 years in this study is similar to the 36.7 years reported in a single center study from southern Nigeria8 and the 35.1 years in Japan 15. Eballe et al,10 however, reported a higher mean age of 43.3 years in a Cameroonian hospital; late presentation for eye care was the reason reported for the high mean age in that study.…”

Section: Discussionsupporting

confidence: 85%

“…RP presents clinically with varied ocular symptoms; night blindness is usually the initial symptom followed by loss of visual field and visual acuity as the disease progresses 1,3,8. It evolves over several decades and final loss of central vision may not occur until the age of 60 years 1,9.…”

Section: Introductionmentioning

confidence: 99%

“…It evolves over several decades and final loss of central vision may not occur until the age of 60 years 1,9. Bilateral blindness of 30% and 50% in RP patients at presentation has been reported in single-center studies in sub-Saharan Africa 8,10. The typical variant of RP remains the most prevalent type globally; atypical RP and RP associated with systemic disorders do occur, although they are not as common as the typical variant 6,11…”

Section: Introductionmentioning

confidence: 99%

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Clinical presentation and visual status of retinitis pigmentosa patients: a multicenter study in southwestern Nigeria

Onakpoya¹,

Adeoti²,

Oluleye³

et al. 2016

OPTH

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BackgroundTo review the visual status and clinical presentation of patients with retinitis pigmentosa (RP).MethodologyMulticenter, retrospective, and analytical review was conducted of the visual status and clinical characteristics of patients with RP at first presentation from January 2007 to December 2011. Main outcome measure was the World Health Organization’s visual status classification in relation to sex and age at presentation. Data analysis by SPSS (version 15) and statistical significance was assumed at P<0.05.ResultsOne hundred and ninety-two eyes of 96 patients with mean age of 39.08±18.5 years and mode of 25 years constituted the study population; 55 (57.3%) were males and 41 (42.7%) females. Loss of vision 67 (69.8%) and night blindness 56 (58.3%) were the leading symptoms. Twenty-one (21.9%) patients had a positive family history, with RP present in their siblings 15 (71.4%), grandparents 11 (52.3%), and parents 4 (19.4%). Forty (41.7%) were blind at presentation and 23 (24%) were visually impaired. Blindness in six (15%) patients was secondary to glaucoma. Retinal vascular narrowing and retinal pigmentary changes of varying severity were present in all patients. Thirty-five (36.5%) had maculopathy, 36 (37.5%) refractive error, 19 (20%) lenticular opacities, and eleven (11.5%) had glaucoma. RP was typical in 85 patients (88.5%). Older patients had higher rates of blindness at presentation (P=0.005); blindness and visual impairment rate at presentation were higher in males than females (P=0.029).ConclusionClinical presentation with advanced diseases, higher blindness rate in older patients, sex-related difference in blindness/visual impairment rates, as well as high glaucoma blindness in RP patients requires urgent attention in southwestern Nigeria.

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Section: Discussionsupporting

confidence: 85%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Clinical presentation and visual status of retinitis pigmentosa patients: a multicenter study in southwestern Nigeria

Onakpoya¹,

Adeoti²,

Oluleye³

et al. 2016

OPTH

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“…Male preponderance was present in the studies reported from Beijing, Denmark and Nigeria. 8,13,17 No statistically significant regional preponderance (rural vs. urban) was noted in the subjects with RP in our study. Notably 2 (15.38%) subjects were relatively asymptomatic whereas others complained of decrease of vision.…”

Section: Discussioncontrasting

confidence: 60%

Prevalence of Retinitis Pigmentosa in South Indian Population Aged Above 40 Years

Sen¹,

Bhargava²,

George³

et al. 2008

Ophthalmic Epidemiology

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“…19 Poor vision is the commonest mode of presentation in Nigeria with over 50% presenting blind. 20 Low visual aids and Braille education remain important sources of visual rehabilitation depending on the level of visual loss.…”

Section: Discussionmentioning

confidence: 99%

Causes of Blindness in a Special Education School

Onakpoya¹,

Adegbehingbe²,

Omotoye³

et al. 2011

West African Journal of Medicine

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BACKGROUND: Blind children and young adults have to overcome a lifetime of emotional, social and economic difficulties. They employ non-vision dependent methods for education. OBJECTIVE: To assess the causes of blindness in a special school in southwestern Nigeria to aid the development of efficient blindness prevention programmes. METHODS: A cross-sectional survey of the Ekiti State Special Education School, Nigeria was conducted in May-June 2008 after approval from the Ministry of Education. All students in the blind section were examined for visual acuity, pen-torch eye examination and dilated fundoscopy in addition to taking biodata and history. RESULTS: Thirty blind students with mean age of 18±7.3 years and male: female ratio of 1.7:1 were examined. Blindness resulted commonly from cataract eight (26.7%), glaucoma six (20%) retinitis pigmentosa four (16.7%) and posttraumatic phthysis bulbi two (6.7%). Blindness was avoidable in 18 (61%) of cases. Glaucoma blindness was associated with redness, pain, lacrimation and photophobia in 15 (50%) and hyphaema in 16.7% of students; none of these students were on any medication at the time of study. CONCLUSION: The causes of blindness in rehabilitation school for the blind are largely avoidable and glaucoma-blind pupils face additional painful eye related morbidity during rehabilitation. While preventive measures and early intervention are needful against childhood cataract and glaucoma, regular ophthalmic consultations and medications are needed especially for glaucoma blind pupils. WAJM 2011; 30(1): 47-50.

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Retinitis pigmentosa in Benin, Nigeria

Abstract: Objectives: To determine the mode of presentation and degree of visual impairment of retinitis pigmentosa in Nigerians. Design: A prospective, non-comparative study.

Cited by 13 publications

References 13 publications

Clinical presentation and visual status of retinitis pigmentosa patients: a multicenter study in southwestern Nigeria

Clinical presentation and visual status of retinitis pigmentosa patients: a multicenter study in southwestern Nigeria

Prevalence of Retinitis Pigmentosa in South Indian Population Aged Above 40 Years

Causes of Blindness in a Special Education School

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