RETRACTED: &amp;lt;i&amp;gt;Usefulness of Iron-Containing Fiducial Marker for Prostate Radiotherapy&amp;lt;/i&amp;gt;

Tanaka, Osamu; Komeda, Hisao; Iida, Takuya; Tamaki, Masayoshi; Seike, Kensaku; Kato, Daisuke; Yokoyama, T.; Hirose, Shigeki; Kawaguchi, Daisuke; Yama, Eiichi

doi:10.4236/ijmpcero.2016.54033

Cited by 2 publications

(4 citation statements)

References 6 publications

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“…Gold FMs are usually cylindrically shaped, with a diameter ranging between 0.5 and 1.5 mm and a length between 2 and 10 mm. Typically, three markers are implanted in the prostate prior to treatment and permanently remain in the target after completion of the treatment (Habermehl et al 2013, Ng et al 2014, Tanaka et al 2016. During treatment planning, the FMs are easily localised on the CT images thanks to their high signal and specific streaking artefacts (Nederveen et al 2000, Habermehl et al 2013, Chan et al 2015.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of an automatic MR-based gold fiducial marker localisation method for MR-only prostate radiotherapy

et al. 2017

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An MR-only radiotherapy planning (RTP) workflow would reduce the cost, radiation exposure and uncertainties introduced by CT-MRI registrations. In the case of prostate treatment, one of the remaining challenges currently holding back the implementation of an RTP workflow is the MR-based localisation of intraprostatic gold fiducial markers (FMs), which is crucial for accurate patient positioning. Currently, MR-based FM localisation is clinically performed manually. This is sub-optimal, as manual interaction increases the workload. Attempts to perform automatic FM detection often rely on being able to detect signal voids induced by the FMs in magnitude images. However, signal voids may not always be sufficiently specific, hampering accurate and robust automatic FM localisation. Here, we present an approach that aims at automatic MR-based FM localisation. This method is based on template matching using a library of simulated complex-valued templates, and exploiting the behaviour of the complex MR signal in the vicinity of the FM. Clinical evaluation was performed on seventeen prostate cancer patients undergoing external beam radiotherapy treatment. Automatic MR-based FM localisation was compared to manual MR-based and semi-automatic CT-based localisation (the current gold standard) in terms of detection rate and the spatial accuracy and precision of localisation. The proposed method correctly detected all three FMs in 15/17 patients. The spatial accuracy (mean) and precision (STD) were 0.9 mm and 0.5 mm respectively, which is below the voxel size of [Formula: see text] mm and comparable to MR-based manual localisation. FM localisation failed (3/51 FMs) in the presence of bleeding or calcifications in the direct vicinity of the FM. The method was found to be spatially accurate and precise, which is essential for clinical use. To overcome any missed detection, we envision the use of the proposed method along with verification by an observer. This will result in a semi-automatic workflow facilitating the introduction of an MR-only workflow.

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Section: Introductionmentioning

confidence: 99%

Evaluation of an automatic MR-based gold fiducial marker localisation method for MR-only prostate radiotherapy

et al. 2017

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“…The GA used in the present study contains 0.5% iron, and its visibility on MRI has been reported to be superior to that of markers containing no iron [ 7 - 9 ]. Tanaka, et al have directly compared the visibility of the GA with a marker containing no iron in the same patient with prostate cancer and reported the superiority of the GA in terms of the detectability on MRI compared with a marker containing no iron in five patients [ 8 - 9 ]. We assessed four patients with liver tumors as an initial report here; further clinical study is needed in order to compare the possible benefits from the features of the GA objectively.…”

Section: Discussionmentioning

confidence: 99%

“…The fiducial marker was percutaneously placed, under local anesthesia, near the tumor by a hepatobiliary surgeon. The GA was 0.28 mm in diameter, 20 mm in length, and had a shape that could be bent to fold the marker [ 8 - 9 ].…”

Section: Technical Reportmentioning

confidence: 99%

“…A 0.5%-iron-containing fiducial marker has been recently reported to have a high visibility in magnetic resonance imaging (MRI) and is possibly superior to markers containing no iron [ 7 - 9 ]. Markers capable of being depicted on MRI can improve contouring of the tumor during treatment planning as liver tumors are often ill-defined on CT.…”

Section: Introductionmentioning

confidence: 99%

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Clinical Implications of a Novel, Iron-containing Fiducial Marker in Radiotherapy for Liver Tumors: An Initial Experience

Doi

Harui

Nakajima

et al. 2017

Cureus

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A 0.5%-iron-containing fiducial marker, Gold AnchorTM (Naslund Medical AB, Huddinge, Sweden), has been recently developed. Herein, we report our initial experiences with the clinical use of the Gold AnchorTM (GA) in radiotherapy for liver tumors. Data of four consecutive patients with liver tumors, including two liver metastases and two hepatocellular carcinomas, were retrospectively analyzed. The GA was percutaneously placed under local anesthesia, close to the tumor. Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging (MRI) was performed after the placement of the GA. Radiotherapy was designed using the volumetric modulated arc therapy technique. All procedures for placement of the GA were successfully performed with no complications. The GA exhibited various forms in the liver in the four patients. All of the GAs were well-detected on MRI, planned computed tomography (CT), and cone-beam CT. Additionally, the tadpole-like shape of the GA showed better detectability than the uptake of lipiodol emulsion and could be used for three-dimensional correlation during setup in daily image-guided radiotherapy. GA was a useful tool in image registration of radiotherapy with a high applicability. Additionally, the tadpole-like shape can be recommended for liver radiotherapy. Our findings suggest that the GA will indeed be useful in clinical practice.

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RETRACTED: <i>Usefulness of Iron-Containing Fiducial Marker for Prostate Radiotherapy</i>

Cited by 2 publications

References 6 publications

Evaluation of an automatic MR-based gold fiducial marker localisation method for MR-only prostate radiotherapy

Evaluation of an automatic MR-based gold fiducial marker localisation method for MR-only prostate radiotherapy

Clinical Implications of a Novel, Iron-containing Fiducial Marker in Radiotherapy for Liver Tumors: An Initial Experience

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