RETRACTED ARTICLE: Synthesis and characterization of CuO nanoparticles and evaluation of their bactericidal and fungicidal activities in cotton fabrics

Alagarasan, D.; Harikrishnan, Adhikesavan; Surendiran, M.; Karuppusamy, Indira; Khalifa, Amany Salah; Elesawy, Basem H.

doi:10.1007/s13204-021-02054-5

Cited by 22 publications

(16 citation statements)

References 31 publications

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“…Metal oxides commonly used for antibacterial purposes include the following: Ag 2 O, ZnO, SiO 2 , CuO, MgO, and CaO [9,10]. Several studies have reported that copper oxide is highly sensitive to Gram-positive (B. subtilis CN2, Candida albicans) and Gram-negative (P. aeruginosa CB1, E. coli) microorganisms [11][12][13]. To enhance the performance of copper oxide (CuO)-based antibacterial materials, surface modifications are usually performed with biocompatible surface-coating materials, such as polymers [14], chitosan [15], and polydopamine (PDA) [16].…”

Section: Introductionmentioning

confidence: 99%

Investigation of the Characteristics and Antibacterial Activity of Polymer-Modified Copper Oxide Nanoparticles

Chen

Liao

Lin

et al. 2021

IJMS

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The proliferation of drug-resistant pathogens continues to increase, giving rise to serious public health concerns. Many researchers have formulated metal oxide nanoparticles for use as novel antibacterial agents. In the present study, copper oxide (CuO) was synthesized by simple hydrothermal synthesis, and doping was performed to introduce different polymers onto the NP surface for bacteriostasis optimization. The polymer-modified CuO NPs were analyzed further with XRD, FTIR, TEM, DLS and zeta potential to study their morphology, size, and the charge of the substrate. The results indicate that polymer-modified CuO NPs had a significantly higher bacteriostatic rate than unmodified CuO NPs. In particular, polydopamine (PDA)-modified CuO (CuO-PDA) NPs, which carry a weakly negative surface charge, exhibited excellent antibacterial effects, with a bacteriostatic rate of up to 85.8 ± 0.2% within 3 h. When compared to other polymer-modified CuO NPs, CuO-PDA NPs exhibited superior bacteriostatic activity due to their smaller size, surface charge, and favorable van der Waals interactions. This may be attributed to the fact that the CuO-PDA NPs had relatively lipophilic structures at pH 7.4, which increased their affinity for the lipopolysaccharide-containing outer membrane of the Gram-negative bacterium Escherichia coli.

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Section: Introductionmentioning

confidence: 99%

Investigation of the Characteristics and Antibacterial Activity of Polymer-Modified Copper Oxide Nanoparticles

Chen

Liao

Lin

et al. 2021

IJMS

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“…The nanoparticles and structures are almost identical in size to biological molecules, which makes them an interesting candidate for biological study in vivo and in vitro (Nienhaus et al, 2020). They would have a wide range of uses in synthetic textiles; biomedical, surgical, and water treatment; equipment; food processing; and packaging (Alagarasan et al, 2021).…”

Section: Deposition Methods Of Nanoparticles On a Fabric Substratementioning

confidence: 99%

Nano-antivirals: A comprehensive review

Hussain

Abro

Ahmed

et al. 2022

Front. Nanotechnol.

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Nanoparticles can be used as inhibitory agents against various microorganisms, including bacteria, algae, archaea, fungi, and a huge class of viruses. The mechanism of action includes inhibiting the function of the cell membrane/stopping the synthesis of the cell membrane, disturbing the transduction of energy, producing toxic reactive oxygen species (ROS), and inhibiting or reducing RNA and DNA production. Various nanomaterials, including different metallic, silicon, and carbon-based nanomaterials and nanoarchitectures, have been successfully used against different viruses. Recent research strongly agrees that these nanoarchitecture-based virucidal materials (nano-antivirals) have shown activity in the solid state. Therefore, they are very useful in the development of several products, such as fabric and high-touch surfaces. This review thoroughly and critically identifies recently developed nano-antivirals and their products, nano-antiviral deposition methods on various substrates, and possible mechanisms of action. By considering the commercial viability of nano-antivirals, recommendations are made to develop scalable and sustainable nano-antiviral products with contact-killing properties.

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“…The inhibitory zone were detected using amphotericin B as a positive control. Three independent assays were conducted [ 26 ].…”

Section: Methodsmentioning

confidence: 99%

Synthesis, Characterization, and Antimicrobial and Antiproliferative Effects of CuO-TiO2-Chitosan-Escin Nanocomposites on Human Leukemic MOLT4 Cells

et al. 2022

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Nanocomposites comprised of CuO-TiO2-chitosan-escin, which has adjustable physicochemical properties, provide a solution for therapeutic selectivity in cancer treatment. By controlling the intrinsic signaling primarily through the mitochondrial signaling pathway, we desired nanocomposites with enhanced anticancer activity by containing CuO-TiO2-chitosan-escin. The metal oxides CuO and TiO2, the natural polymer chitosan, and a phytochemical compound escin were combined to form CuO-TiO2-chitosan-escin nanocomposites. The synthesized nanocomposites were confirmed and characterized using FTIR spectroscopy, TEM, and UV-Vis absorption spectroscopy. A human leukemia cell line (MOLT-4) was used to assess the efficacy and selectivity of nanocomposites. Based on a cytotoxicity study, CuO-TiO2-chitosan-escin nanocomposites had inhibition concentrations (IC50) of 13.68, 8.9, and 7.14 µg/mL against human T lymphoblast cells after 24, 48, and 72 h of incubation, respectively. Compared with untreated MOLT-4 cells, CuO-TiO2-chitosan-escin nanocomposite-treated cells significantly increased (p < 0.05) caspase-3, -8, and -9 and decreased the levels of antioxidant enzymes GR, SOD, and GSH. Furthermore, MDA for lipid peroxidase and ROS levels significantly increased (p < 0.05) in the treated cells than in the untreated cells. Remarkably, CuO-TiO2-chitosan-escin nanocomposite-mediated control of cell cycles were mainly achieved through the activation of caspase-3, -8, and -9.

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RETRACTED ARTICLE: Synthesis and characterization of CuO nanoparticles and evaluation of their bactericidal and fungicidal activities in cotton fabrics

Cited by 22 publications

References 31 publications

Investigation of the Characteristics and Antibacterial Activity of Polymer-Modified Copper Oxide Nanoparticles

Investigation of the Characteristics and Antibacterial Activity of Polymer-Modified Copper Oxide Nanoparticles

Nano-antivirals: A comprehensive review

Synthesis, Characterization, and Antimicrobial and Antiproliferative Effects of CuO-TiO2-Chitosan-Escin Nanocomposites on Human Leukemic MOLT4 Cells

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