RETRACTED: The Use of Tooth Particles as a Biomaterial in Post-Extraction Sockets. Experimental Study in Dogs

Abstract

Objectives: The objective of this study was to evaluate new bone formation derived from freshly crushed extracted teeth, grafted immediately in post-extraction sites in an animal model, compared with sites without graft filling, evaluated at 30 and 90 days. Material and Methods: The bilateral premolars P2, P3, P4 and the first mandibular molar were extracted atraumatically from six Beagle dogs. The clean, dry teeth were ground immediately using the Smart Dentin Grinder. The tooth particles obtained were subsequently sieved through a special sorting filter into two compartments; the upper container isolating particles over 1200 μm, the lower container isolated particles over 300 μm. The crushed teeth were grafted into the post-extraction sockets at P3, P4 and M1 (test group) (larger and smaller post-extraction alveoli), while P2 sites were left unfilled and acted as a control group. Tissue healing and bone formation were evaluated by histological and histomorphometric analysis after 30 and 90 days. Results: At 30 days, test site bone formation was greater in the test group than the control group (p < 0.05); less immature bone was observed in the test group (25.71%) than the control group (55.98%). At 90 days, significant differences in bone formation were found with more in the test group than the control group. No significant differences were found in new bone formation when comparing the small and large alveoli post-extraction sites. Conclusions: Tooth particles extracted from dog’s teeth, grafted immediately after extractions can be considered a suitable biomaterial for socket preservation.

Prevention of Periodontal Pocket Formation after Mandibular Third Molar Extraction Using Dentin Autologous Graft: A Split Mouth Case Report

“…Calvo-Guirado et al, in a study on beagle dogs, hystologically demonstrated the formation of new well-organized bone, with multiple osteons at 90 days after dentin autograft. Hystomorphometry revealed the presence of higher percentages of mature bone and less percentages of immature bone in the sites grafted with particulated dentin when compared with no-grafted sites at 90 days [ 23 ].…”

“…Immediately after the extraction ( Figure 1 ), the right molar's fragments were grinded for 3 seconds (300-1200 μ m) by the use of the Smart Dentin Grinder™ (KometaBio, Fort Lee, NJ, USA) and then immersed into a 0.5 M NaOH and 20% ethanol solution for 10 minutes, in order to dissolve all the organic remains from the tubules. The particulate was first dried with a sterile gauze, then rinsed two times (3 minutes each) with phosphate-buffered saline solution to remove all the NaOH and the ethanol [ 16 , 23 ]. The right postextractive socket (test site) was filled with the grinded dentin; then, the left one (control site) was filled with a fibrin sponge.…”

RETRACTED: Calvo-Guirado et al. The Use of Tooth Particles as a Biomaterial in Post-Extraction Sockets. Experimental Study in Dogs. Dent. J. 2018, 6, 12

“…We have been made aware that Figure 7d of paper [ 1 ] is similar to Figure 11a of a paper published in Applied Sciences [ 2 ]. Both figures show histological images from dogs for experiments carried out in different research projects.…”

“…The authors were unable to provide an adequate explanation for the similarity. The Editor-in-Chief and the Editorial Office have therefore taken the decision to retract the paper [ 1 ].…”

“…The Dentistry Journal Editorial Office apologize to the readers of the Dentistry Journal for any inconvenience caused. To ensure the addition of only high-quality scientific works to the field of scholarly communication, this paper [ 1 ] is retracted and shall be marked accordingly. MDPI is a member of the Committee on Publication Ethics (COPE) and takes very seriously the responsibility to enforce strict ethical policies and standards.…”