Retraction notice to “Toward an optimal oligosaccharide ligand for rat natural killer cell activation receptor NKR-P1” [Biochem. Biophys. Res. Commun. 287 (2001) 11–20]

Krist, Pavel; Herkommerová-Rajnochová, Eva; Rauvolfová, Jana; Semeňuk, Tomáš; Vavrušková, Petra; Pavlíček, Jiří; Bezouška, Karel; Petruš, Ladislav; Křen, Vladimı́r

doi:10.1016/j.bbrc.2014.10.099

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Applications Of Calixarenes In Drug Discovery1

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“…172 The binding affinity of GlcNAc-substituted calix [4]arenes carrying two to four sugar units were in good agreement with the inhibitory potencies of the linear chitooligomers (chitobiose to chitotetraose) reported previously by the same group. 173,174 The influence of GlcNAc substitution of the calix [4]arene skeleton on binding affinity for the CD69 receptor was more profound and the GlcNAc-terasubstituted calix [4]arene 100 proved to be the best CD69 ligand. Lower GlcNAc substitution led to a substantial decrease of the binding activity.…”

Section: Applications Of Calixarenes In Drug Discoverymentioning

confidence: 99%

Biological applications of functionalized calixarenes

Nimse

Kim²

2013

Chem. Soc. Rev.

372

256

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The functionalized calixarene derivatives exhibit remarkable properties towards organic and bioorganic molecules. However, the ability of calixarene derivatives to form stable complexes with biomolecules allows them to be applied for the development of biosensors and in the field of biology, biotechnology, and drug discovery. The applications of the functionalized calixarenes are summarized in this review, and an outlook for the future developments is discussed. A brief survey (of the last 10 years) on their biological application in various fields is also considered (199 references).

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