Retroperitoneal ancient schwannoma presenting as an adrenal incidentaloma: CT and MR findings

Inokuchi, Taku; Takiuchi, Hidekazu; Moriwaki, Yuji; Ka, Tsuneyoshi; Takahashi, Sumio; Tsutsumi, Zenta; Shima, Hiroki; Hirota, Seiichi; Yamamoto, Tetsuya

doi:10.1016/j.mri.2006.07.015

Cited by 52 publications

(31 citation statements)

References 14 publications

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“…The accuracy, sensitivity and specificity of FNA in mesenchymal tumors have been reported at approximately 90%, showing that FNA may be used with precision for preoperative evaluation [7] On MRI, the ancient schwannoma shows well-circumscribed, homogeneous signal intensity and a different enhancement pattern. According to the findings of Isobe and colleagues [8], the circumferences of the degenerated area and fibrous tumour capsule enhanced on MRI are important for discriminating an ancient schwannoma from other tumours [9,10]. Our case showed hypointense fibrous capsules and enhancements.…”

Section: Discussionsupporting

confidence: 54%

Mri and Fnac Are Useful Tools in Pre-Operative Diagnosis of Ancient Schwannoma: A Case Report

C.V¹,

Sujai²,

R³

et al. 2013

jemds

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Section: Discussionsupporting

confidence: 54%

Mri and Fnac Are Useful Tools in Pre-Operative Diagnosis of Ancient Schwannoma: A Case Report

C.V¹,

Sujai²,

R³

et al. 2013

jemds

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“…9 On MRI, the schwannoma shows low signal intensity on T1-weighted images and heterogeneous high signal intensity on T2-weighted images. 3,[6][7][8][9][10] The heterogeneous high signal intensity on T2-weighted images can be attributed to the alternating Antoni A and B areas, which will be discussed in more detail in the histopathology section. 9 Both CT and MRI are nonspecific in regard to the diagnosis of adrenal schwannomas.…”

Section: Clinical Featuresmentioning

confidence: 99%

Adrenal Schwannoma: A Rare Type of Adrenal Incidentaloma

Mohiuddin

Gilliland

2013

Archives of Pathology &Amp; Laboratory Medicine

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Adrenal schwannoma is a rare type of adrenal incidentaloma, an adrenal lesion found incidentally, usually on imaging or autopsy. Computed tomography and magnetic resonance imaging are tools used to evaluate adrenal lesions. The diagnosis of adrenal schwannoma, however, cannot be made on imaging alone. Surgical resection is the primary means of management of adrenal schwannomas, as it is not possible to distinguish the schwannoma from malignant entities simply based on imaging. Histopathologic features of adrenal schwannomas are similar to those of schwannomas found at other sites. Conventional schwannomas, consisting of alternating Antoni A and Antoni B areas as well as Verocay bodies, have distinct microscopic features and can be readily distinguished from other entities. Cellular schwannomas, on the other hand, consist only of intersecting fascicles of spindle cells or Antoni A areas, resulting in a wide differential diagnosis. Ancillary studies such as immunohistochemical analysis and electron microscopy can help to provide a specific diagnosis.

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“…1 Laboratory investigations for schwannoma are unremarkable and do not contribute to diagnosis. 4 There are different imaging modalities that may aid in the differential diagnosis of retroperitoneal schwannomas, such as ultrasonography, CT-scan and MRI. 1,5 The various lesions that can occur in these regions can be an adenoma of the adrenal gland, pheochromocytoma, myelolipoma, metastasis, neurofibroma, paraganglioma, lipoma and malignant fibrous histiocytoma.…”

Section: Discussionmentioning

confidence: 99%

Retroperitoneal Schwannoma mimicking a Large Adrenal Incidentaloma: Case Report and Review of Literature

Shabiyullah¹,

Singaporewalla²,

Rao³

et al. 2014

World Journal of Endocrine Surgery

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Schwannomas are rare tumors originating from Schwann cells of peripheral nerve sheath (neurilemma) of the ectoderm. They are also referred to as neurilemmomas and are generally be nign, solitary tumors arising from cranial and peripheral nerves. Rarely, they arise from the retroperitoneum and adrenal medulla. Retroperitoneal schwannomas constitute about 0.5 to 5% of all schwannomas and of which most of them are benign in nature. Most patients are asymptomatic or have vague abdominal symp toms. On imaging, they are often mistaken for adrenal tumors due to their location and preoperative diagnosis is often difficult. Magnetic resonance imaging (MRI) is the investigation of choice to demonstrate these lesions and its relation to other structures. Total excision is recommended as malignancy, although rare cannot be ruled out preoperatively. We present a case of a large retroperitoneal schwannoma that mimicked an adrenal incidentaloma and was excised laparoscopically. The imaging characteristics and management strategy are discussed.

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Retroperitoneal ancient schwannoma presenting as an adrenal incidentaloma: CT and MR findings

Cited by 52 publications

References 14 publications

Mri and Fnac Are Useful Tools in Pre-Operative Diagnosis of Ancient Schwannoma: A Case Report

Mri and Fnac Are Useful Tools in Pre-Operative Diagnosis of Ancient Schwannoma: A Case Report

Adrenal Schwannoma: A Rare Type of Adrenal Incidentaloma

Retroperitoneal Schwannoma mimicking a Large Adrenal Incidentaloma: Case Report and Review of Literature

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