Retroperitoneal cyst and congenital absence of ipsilateral kidney

Benign Cystic Mesothelioma Associated with Ipsilateral Renal Agenesis: A Case Report and Review of Literature

“…Additionally, immunostaining is positive for vascular markers such as CD31 and CD34 [6] and negative for cytokeratin [7]. Mullerian cysts are lined by serous or mucinous epithelium [6], Immunostaining of the cyst lining is Pax8 positive [10] and CD 10 negative [8], Urogenital cysts are lined by cuboidal to columnar epithelium [2,11]. The walls contain fibrous tissue and smooth muscle, and primitive renal structures may be present [11].…”

“…Mullerian cysts are lined by serous or mucinous epithelium [6], Immunostaining of the cyst lining is Pax8 positive [10] and CD 10 negative [8], Urogenital cysts are lined by cuboidal to columnar epithelium [2,11]. The walls contain fibrous tissue and smooth muscle, and primitive renal structures may be present [11]. Malignant mesothelioma can be distinguished from BCM by the presence of stromal invasion [5], high cellularity, nuclear atypia, and mitotic activity [5][6][7].…”

“…Without stimulation from the ureteric bud, the metanephrogenic cap does not form normal renal tissue [11]. Thus, congenital absence of the kidney often results in ipsilateral absence of the ureter [11], The single kidney undergoes compensatory glomerular hyperfiltration, lead ing to renal injury that presents at a median age of 15 years [11]. A review by Westland and coworkers revealed that hypertension was present in 16% of patients with unilateral renal agenesis [13].…”

“…Devaraju and colleagues reported renal agenesis associ ated with mullerian cysts in a 28-year-old woman [14], and Hodgins and Hancock reported metanephric cysts associated with renal agenesis in a 30-year-old man [11], However, only 3 cases of BCM associated with various congenital renal abnormalities have been reported, and all occurred in pediatric patients [1,4]. One paper reported contralateral renal agenesis associated with BCM in an 11-year-old boy [1] and the other 2 reported an extrarenal pelvis and a horseshoe kidney in adolescent females [4], Perhaps the positive immunostaining with WT-1 in our case might explain this association.…”

“…Immunostaining of the cyst lining is Pax8 positive [10] and CD10 negative [8]. Urogenital cysts are lined by cuboidal to columnar epithelium [2,11]. The walls contain fibrous tissue and smooth muscle, and primitive renal structures may be present [11].…”