Retroperitoneal Extraskeletal Osteosarcoma: Imaging Findings and Transarterial Chemoembolization

Abstract

Extraskeletal osteosarcoma (EOS) is an uncommon and usually highly aggressive mesenchymal tumor. Retroperitoneal extraskeletal osteosarma (REOS) is exceedingly rare. Due to the rare nature of the disease, both the diagnosis and the management of REOS can be challenging. We present the clinical history, CT findings, angiographic manifestations, and use of transarterial chemoembolization for treatment in a case of REOS. To our knowledge, the angiographic features of and attempt at transarterial treatment of REOS have not been reported in the literature.

Gastric wall implantation metastasis of retroperitoneal extraskeletal osteosarcoma: A case report and review of the literature

“…ESOS represents <4% of all osteosarcomas and 1–2% of all soft-tissue sarcomas ( 1 – 3 ). There is a male bias for osteosarcoma, and the gender ratio is 1.9:1.0 ( 2 ).…”

“…Extraskeletal osteosarcoma (ESOS) is a rare and highly invasive tumor ( 1 – 3 , 5 – 8 ). Retroperitoneal ESOS is usually diagnosed at an advanced stage due to the insidious onset ( 2 – 9 ).…”

Primary duodenal extraskeletal osteosarcoma-a case report

“…The patient had an uneventful post operative period and remains free of tumor a year after surgery. doi: 10.7243/2055-091X-1-9 have been less than 50 cases reported so far [5]. Usually affects adults with a high incidence in patients older than 50 years and is slightly more common in males than in female patients [1].…”

“…Nevertheless, the major predictor of clinical outcome was found to be the tumour size (>5cm) according to the study by Bane et al [4]. According to ED B Chung and F M Enzinger, extraskeletal osteosarcoma with a prominent fibroblastic or MFH like component seemed to have a slightly better prognosis than predominantly osteoblastic, chondroblastic or telangiectatic types of the tumour [5]. The biological behaviour of well differentiated extraskeletal osteosarcoma has been suggested to be better than that of classical extraskeletal osteosarcoma, but some cases can progress to a higher grade [7].…”

“…According to a study by Lee JS and et al, patients with extraskeletal osteosarcoma generally have a poor prognosis and the majority develops metastatic disease within 3 years of diagnosis [12,13]. It has been reported that the overall mortality rates due to the tumor in the larger series exceeded 60% [1,2,5]. Radical resection appears to be the best therapeutic option for local control but has no effect on distant metastasis [14].…”