2018
DOI: 10.1016/j.lrr.2018.07.001
|View full text |Cite
|
Sign up to set email alerts
|

Retrospective analysis of primary plasma cell leukemia in Kansai Myeloma Forum registry

Abstract: HighlightsThe prevalence of pPCL was 1.2%.Treatment with novel agents and transplantation may yield a better prognosis.Hypercalcemia at diagnosis was suggested to predict worse outcomes.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2019
2019
2024
2024

Publication Types

Select...
4

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(2 citation statements)
references
References 12 publications
0
2
0
Order By: Relevance
“…In summary, taking into consideration the outcomes of pPCL patients treated frontline with novel agents [ 15 , 17 , 27 , 28 , 40 42 , 59 64 ], following Musto et al [ 36 ] ( Table 2 ), particularly bortezomib and lenalidomide induce an overall response rate (ORR) ranging from 57% to 87%, with up to 45% CR. The OS in young patients undergoing transplantation ranges from 16 to 61 months, while in elderly transplant-ineligible individuals it varies between 12 and 28 months.…”
Section: Primary Plasma Cell Leukemiamentioning
confidence: 99%
“…In summary, taking into consideration the outcomes of pPCL patients treated frontline with novel agents [ 15 , 17 , 27 , 28 , 40 42 , 59 64 ], following Musto et al [ 36 ] ( Table 2 ), particularly bortezomib and lenalidomide induce an overall response rate (ORR) ranging from 57% to 87%, with up to 45% CR. The OS in young patients undergoing transplantation ranges from 16 to 61 months, while in elderly transplant-ineligible individuals it varies between 12 and 28 months.…”
Section: Primary Plasma Cell Leukemiamentioning
confidence: 99%
“…Abnormal plasma cells are observed in the PB at the initial presentation in pPCL, whereas they are observed in the PB during the clinical course of MM in sPCL (1-3). The prognosis of pPCL has been reported to be very poor, and the median overall survival (OS) has been reported to be four to six months (4,5). Thus, the early, accurate diagnosis is required for the proper management of PCL.…”
Section: Introductionmentioning
confidence: 99%