Retrovirus endógenos humanos: Significado biológico e implicaciones evolutivas

Sentís, C.

doi:10.3989/arbor.2002.i677.1073

Cited by 2 publications

(5 citation statements)

References 76 publications

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“…It is currently known that the information of the ERVs contained in our cells is so important that without it the eukaryotic cells would not be able to perform many of their vital functions. Linear chromosomes, telomeres, transcription and translation processes originate from genes that we consider ERVs [13][14][15][16][17].…”

Section: Are the Ervs Genetic Materials Accumulated In Our Genome?mentioning

confidence: 99%

“…However, it does not make sense that the remains of an infectious material were perpetuated millions of years within our genome if they did not fulfill some function. Evolutionary pressure would simply rule them out [13,14].…”

Section: Are the Ervs Genetic Materials Accumulated In Our Genome?mentioning

confidence: 99%

“…How could it be explained that viral genes are permanently introduced into the genome of evolutionarily superior cells and produce important improvements in their physiology? [13][14][15][16][17].…”

Section: Are the Ervs Genetic Materials Accumulated In Our Genome?mentioning

confidence: 99%

“…The ERVs "Syncytin" is of vital importance in the normal architectural development of the placenta, especially in the process of fusion of the cytotrophoblasts with the syncytotrophoblasts, to the point that their dysfunction produces diseases such as pre-eclamsia or the HELLP syndrome [17]. American scientists discovered the surprising ability of ERVs to activate the totipotential state of stem cells [13]. By adding these viral genes, the cells reverted to a more plastic and more developmental state.…”

Section: Are the Ervs Genetic Materials Accumulated In Our Genome?mentioning

confidence: 99%

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Viruses: Genetically encoded alarm messages for communication between individuals

Sousa¹

2020

Clin Microbiol Infect Dis

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According to the present alert information theory, viruses are not microorganisms external to our body, but their genetic material is already contained in the DNA/ RNA of our cells, in what we know as Endogenous Retroviruses (ERVs). A virus would actually be an Exogenous Cellular Gene Secretion (ECGS) carrying alert information that would be produced by cells under stress. They are made up of DNA or RNA genes wrapped in a protein capsule and, in some cases, a protective membrane. Such coatings would allow them to withstand the conditions of displacement within the organism, or between different individuals, and possess a form of binding to transmit their information to a specific recipient cell.Finally, the Extracellular Vesicles (EVs) secreted after the entry of these ECGS in the target cells, would perform, among other functions, that of second messengers of the viral message from abroad, defining the immune response of the receptor.

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Section: Are the Ervs Genetic Materials Accumulated In Our Genome?mentioning

confidence: 99%

Section: Are the Ervs Genetic Materials Accumulated In Our Genome?mentioning

confidence: 99%

Section: Are the Ervs Genetic Materials Accumulated In Our Genome?mentioning

confidence: 99%

Section: Are the Ervs Genetic Materials Accumulated In Our Genome?mentioning

confidence: 99%

See 2 more Smart Citations

Viruses: Genetically encoded alarm messages for communication between individuals

Sousa¹

2020

Clin Microbiol Infect Dis

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“…Therefore, evolutionary processes could be enhanced due to ecophysiological stress (i.e., species adaptations are often pushed to the limit; Brown 1984;Brussard 1984;Case et al 2005) and the genetic differentiation caused by isolation. In addition, it is known that environmental stress increases retrotransposon activity (see Sentís 2002), favoring symbiotic interactions (e.g., Russell et al 2003), and promoting lateral gene transmission (see Nieto et al 2004). In addition, many species may survive human disturbance or climate change in a given region (threatened or at range-margins) by adapting new life-history strategies, such as the modification of their micro-distributions and/or near environment (e.g.…”

Section: Detection Of Evolutionarily Important Areas Speciesmentioning

confidence: 99%

A synecological framework for systematic conservation planning

Hortal

Lobo

2006

Biodiv. Inf.

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Abstract.− Biodiversity conservation design, though difficult with fragmentary or insufficient biological data, can be planned and evaluated with several methods. One of them, the complementarity criterion, is commonly used to account for the distributions of a number of species (i.e., an autoecological approach). At the same time, the patchiness and spatial bias of available distribution data has also been dealt with through distribution modelling. However, both the uncertainty of the ranges estimated and the changes in species' distributions in response to changing climates, limit the potential of single-species distributions as the biodiversity attribute to be used in complementarity strategies. Several technical and theoretical advantages of composite biodiversity variables (i.e., a synecological approach) may, however, make them ideal biodiversity indicators for conservation area selection. The drawbacks associated with current biodiversity data are discussed herein, along with the possible advantages and disadvantages of conservation planning through a synecological or autoecological approach.

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Retrovirus endógenos humanos: Significado biológico e implicaciones evolutivas

Cited by 2 publications

References 76 publications

Viruses: Genetically encoded alarm messages for communication between individuals

Viruses: Genetically encoded alarm messages for communication between individuals

A synecological framework for systematic conservation planning

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