Reuse of Clinical Information: Integrating Primary Care and Clinical Research through a Bidirectional Standard Interface

Fraccaro, Paolo; Pupella, Valeria; Gazzarata, Roberta

doi:10.1007/978-3-319-00846-2_315

Cited by 2 publications

(2 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…a During the first year, the platform supported several regional and national studies. 18 However, frequent use of the platform led to the rise of well-known problems caused by manual data input. [19][20][21] First, the huge amount of time required to insert even a minimal set of data necessary to conduct a clinical trial.…”

Section: Background and Significancementioning

confidence: 99%

Ten Years of Medical Informatics and Standards Support for Clinical Research in an Infectious Diseases Network

et al. 2023

Self Cite

View full text Add to dashboard Cite

Background It is 30 years since evidence-based medicine became a great support for individual clinical expertise in daily practice and scientific research. Electronic systems can be used to achieve the goal of collecting data from heterogeneous datasets and to support multicenter clinical trials. The Ligurian Infectious Diseases Network (LIDN) is a web-based platform for data collection and reuse originating from a regional effort and involving many professionals from different fields. Objectives The objective of this work is to present an integrated system of ad hoc interfaces and tools that we use to perform pseudonymous clinical data collection, both manually and automatically, to support clinical trials. Methods The project comprehends different scenarios of data collection systems, according to the degree of information technology of the involved centers. To be compliant with national regulations, the last developed connection is based on the standard Clinical Document Architecture Release 2 by Health Level 7 guidelines, interoperability is supported by the involvement of a terminology service. Results Since 2011, the LIDN platform has involved more than 8,000 patients from eight different hospitals, treated or under treatment for at least one infectious disease among human immunodeficiency virus (HIV), hepatitis C virus, severe acute respiratory syndrome coronavirus 2, and tuberculosis. Since 2013, systems for the automatic transfer of laboratory data have been updating patients' information for three centers, daily. Direct communication was set up between the LIDN architecture and three of the main national cohorts of HIV-infected patients. Conclusion The LIDN was originally developed to support clinicians involved in the project in the management of data from HIV-infected patients through a web-based tool that could be easily used in primary-care units. Then, the developed system grew modularly to respond to the specific needs that arose over a time span of more than 10 years.

show abstract

Section: Background and Significancementioning

confidence: 99%

Ten Years of Medical Informatics and Standards Support for Clinical Research in an Infectious Diseases Network

et al. 2023

Self Cite

View full text Add to dashboard Cite

show abstract

“…So, all doctors in the network can use their data either to perform local clinical trial or to participate to national and international observational studies. Therefore, this repository contains well assessed and standardized clinical information [5].…”

Section: Introductionmentioning

confidence: 99%

Standards for the Reuse of Clinical Data in Research: the Connection of the Liguria HIV Network and the CISAI Cohort

Bonetto¹,

Mora

Maggi

et al. 2019

2019 Global Medical Engineering Physics Exchanges/ Pan American Health Care Exchanges (GMEPE/PAHCE)

View full text Add to dashboard Cite

Reuse of Clinical Information: Integrating Primary Care and Clinical Research through a Bidirectional Standard Interface

Cited by 2 publications

References 7 publications

Ten Years of Medical Informatics and Standards Support for Clinical Research in an Infectious Diseases Network

Ten Years of Medical Informatics and Standards Support for Clinical Research in an Infectious Diseases Network

Standards for the Reuse of Clinical Data in Research: the Connection of the Liguria HIV Network and the CISAI Cohort

Contact Info

Product

Resources

About