1993
DOI: 10.1038/eye.1993.178
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Reversal of lipaemia retinalis with dietary control

Abstract: Lipaemia retinalis occurs as the result of a marked elevation of serum lipids. Combined hyperlipidaemia may occur as a primary familial or secondary acquired abnormality. A case of lipaemia retinalis is described, documented by fundus photographs. A complete lipid profile of the patient revealed marked hyperlipidaemia. The lipoprotein lipase level was found to be reduced 0.3 cu (normal 0.5-2.0 cu). The patient was put on a low-fat diet, after which serial fundus photographs showed an improvement in the fundus … Show more

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Cited by 9 publications
(9 citation statements)
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“…[21][22][23] In addition, a case of lipoprotein lipase deficiency coupled with high dietary fat intake presented normal fluorescein angiography, visual fields, and visual acuity. 24 However, another case report involving a patient with most likely primary mixed hyperlipidemia and secondary diabetes mellitus did report a decrease in visual acuity, but it was attributed to diabetic macular edema and not lipemia retinalis. 25 Treatment for lipemia retinalis involves treating the cause of hypertriglyceridemia with the main goal of maintaining fasting triglyceride levels at , 500 mg/dL to reduce the risk of acute pancreatits.…”
Section: Discussionmentioning
confidence: 96%
“…[21][22][23] In addition, a case of lipoprotein lipase deficiency coupled with high dietary fat intake presented normal fluorescein angiography, visual fields, and visual acuity. 24 However, another case report involving a patient with most likely primary mixed hyperlipidemia and secondary diabetes mellitus did report a decrease in visual acuity, but it was attributed to diabetic macular edema and not lipemia retinalis. 25 Treatment for lipemia retinalis involves treating the cause of hypertriglyceridemia with the main goal of maintaining fasting triglyceride levels at , 500 mg/dL to reduce the risk of acute pancreatits.…”
Section: Discussionmentioning
confidence: 96%
“…Hypercholesterolemia alone does not produce retinal changes [12]. Patients with lipemia retinalis in typical cases maintain good vision, and fundus changes resolve when serum lipid levels are reduced [2,13]. However, it was shown in a rabbit model of hypercholesterolemia that normalization of serum cholesterol levels was not enough to reverse cholesterol-induced vascular damage to the choroid and retinal vessels.…”
Section: Discussionmentioning
confidence: 99%
“…Die häufigste Ursache einer Lipaemia retinalis im Rahmen einer sekundären Hyperlipidämie ist eine diabetische Stoffwechselentgleisung [5,6]. Bei unserer Patientin führte das klassische Bild eines metabolischen Syndroms (Fehlernährung, Insulinresistenz, essentielle Hypertonie) getriggert durch eine Steatosis hepatis und eine chronische Pankreasinsuffizienz bei Alkoholabusus zu einer exzessiven gemischten Hyperlipoproteinämie und damit zum ophthalmoskopischen Bild einer Lipaemia retinalis.…”
Section: Diskussionunclassified
“…Bei unserer Patientin führte das klassische Bild eines metabolischen Syndroms (Fehlernährung, Insulinresistenz, essentielle Hypertonie) getriggert durch eine Steatosis hepatis und eine chronische Pankreasinsuffizienz bei Alkoholabusus zu einer exzessiven gemischten Hyperlipoproteinämie und damit zum ophthalmoskopischen Bild einer Lipaemia retinalis. Triglyzeridämien sind im Vergleich zu anderen Hyperlipoproteinämien diätetisch gut zu regulieren [5,8]. Eine lipidsenkende Therapie kann nicht nur kardiovaskuläre Ereignisse, sondern auch Komplikationen an peripheren Gefäûen vermindern [3,8].…”
Section: Diskussionunclassified
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