Reversal of nail changes after liver transplantation in a child

Gandhi, Vidhyachandra; Nagral, Aabha; Philip, Sujith; Malkani, Ram H; Pimputkar, Rujuta

doi:10.1007/s12664-009-0054-8

Cited by 4 publications

(3 citation statements)

References 6 publications

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“…In fact, the aortic stenosis may lead to a defective larger reversible polymer von Willebrand factor (exposed to high flow through the stenotic aortic valve) and explain the association with intestinal bleeding especially the venous ectasia, already frequent in the elderly. For this reason, some authors reported a complete remission of bleeding after aortic valve replacement, so as to offer surgery as the choice of therapy (22)(23)(24)(25)(26)(27).…”

Section: Discussionmentioning

confidence: 99%

An Unclear Anemia in an Elderly Subject with Aortic Stenosis

Magro

2015

Electron J Gen Med

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Section: Discussionmentioning

confidence: 99%

An Unclear Anemia in an Elderly Subject with Aortic Stenosis

Magro

2015

Electron J Gen Med

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“…Onycholysis ( Figure 2(f) ) is the detachment of the nail bed from the overlying nail plate and may be due to trauma, manicuring and photodermatitis. While psoriasis is the most prevalent disease leading to onycholysis [ 47 ], there is also a significant association between liver cirrhosis and onycholysis, which have been reported to resolution following liver transplant [ 48 ].…”

Section: Vascular Alterationsmentioning

confidence: 99%

Recognizing skin conditions in patients with cirrhosis: a narrative review

Liu

Gao

et al. 2022

Annals of Medicine

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Background: The skin is a major target organ for extrahepatic manifestations of liver diseases, and dermatologic abnormalities are common in patients with hepatic disorders. Clinical examination of the skin, nails and hair can allow for appropriate recognition, early diagnosis and treatment of liver diseases, and improvement in the quality of life and life expectancy of affected patients. Methods: We searched 3 databases (Pubmed,Medline and Embase) and selected studies about cirrhosis related skin manifestations and their pathophysiology. Results: A total of 73 articles were included in the review. Studies displayed the spectrum of cutaneous manifestations related to hormonal and vascular changes as well as nail and hair changes in patients with cirrhosis and/or portal hypertension. Conclusion: Cutaneous alterations are important clues or potential indications in the diagnosis of liver cirrhosis. Familiarity with skin conditions can be promptly diagnosed and appropriate management initiated. KEY MESSAGES Manifestations of the liver and skin disorders are interrelated in various ways. Cutaneous changes may be the first clue that a patient has liver disease. The skin is a major target organ for extrahepatic manifestations of liver diseases. A broad range of cutaneous alterations can be present in patients with cirrhosis, such as vascular, nail, hair, hormonal changes, etc. Recognizing these signs is crucial so that potential underlying diseases including liver disease can be promptly diagnosed and appropriate management timely initiated.

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“…Various nail changes have been described in patients of liver cirrhosis including Terry's nails, leukonychia, dystrophic nails, onychorrhexis, as well as onycholysis and clubbing. Reversal of these changes after liver transplantation have been described in a pediatric patient, 1 in an adult with primary biliary cirrhosis 2 and in 11 adult patients with cirrhosis 3 . There is paucity of knowledge about the pathophysiology of these changes, but changes in nail bed vascularity and overgrowth of connective tissue has been postulated as a mechanism for occurrence of terry's nails 4 .…”

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confidence: 99%