REVIEW: Ellagitannin; biosynthesis, isolation, and biological activities

Hidyarko, Akmalia Imbi Febriyanti; Gayatri, Aldila Cahya; Rifa, Vira Ainu; Indrawan, Muhamad; Setyawan, Ahmad Dwi

doi:10.13057/biofar/f010105

Cited by 6 publications

(5 citation statements)

References 27 publications

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“…adanya kandungan tanin ini yang dapat menyebabkan rasa dari kulit manggis sehingga menjadi pahit. Akan tetapi senyawa tanin pada umumnya dapat larut dengan pelarut dari polar seperti Etanol sampai semi polar, sehingga hal ini tidak berpengaruh terhadap rasa uji organoleptik penambahan ekstrak kulit manggis terhadap pengolahan terasi (Hernawan dan Setyawan, 2003).…”

Section: Rasaunclassified

PENAMBAHAN EKSTRAK KULIT MANGGIS (Garcinia mangostana. L) DENGAN KOMPOSISI BERBEDA SEBAGAI PEWARNA ALAMI DALAM PENGOLAHAN TERASI BUBUK

Riyadi¹,

Wiranata²,

Jaya³

2020

J. ilmu-ilmu perikan. budid. perair.

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Terasi merupakan bumbu tradisional yang banyak disukai oleh masyarakat. Permasalahan penggunaan pewarna buatan terasi diduga dapat diatasi dengan penambahan ekstrak kulit manggis (Garcinia mangostana. L) yang kaya akan anthosianin. Perlakuan pada penelitian ini berupa penambahan Ekstrak Kulit Manggis pada pengolahan terasi dengan berbagai konsentrasi (B/B) yaitu : 0 %, 2.5 %, 5 %, 7.5 %, 10 % (dari berat bahan baku). Nilai analisa fisik dari hasil terasi bubuk terbaik terdapat pada perlakuan penambahan ekstrak kulit manggis 10 % (W5) dengan nilai lightness 47.61, chroma 27.11 dan hue 50.01. Nilai mutu organoleptik terasi bubuk terbaik terdapat pada perlakuan penambahan ekstrak kulit manggis 10 % (W5) dengan nilai warna 3.76 %, penampakan 3.60 %, aroma 3.52 %, rasa 3.60 %. Nilai mutu kimia terasi bubuk terbaik berdasarkan nilai mutu fisik dan organoleptik terbaik adalah kadar air 19.75%, abu 11.14%, protein 40.41%, lemak 2.00 %, karbohidrat 26.30 %.

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Section: Rasaunclassified

PENAMBAHAN EKSTRAK KULIT MANGGIS (Garcinia mangostana. L) DENGAN KOMPOSISI BERBEDA SEBAGAI PEWARNA ALAMI DALAM PENGOLAHAN TERASI BUBUK

Riyadi¹,

Wiranata²,

Jaya³

2020

J. ilmu-ilmu perikan. budid. perair.

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“…At the same time, tannin compounds such elagitanin and elagat acid are known to have hypoglycemic activity. Thus, it can minimize protein glycation [36] . Based on the results, it can be expected that PTR-21 extract has the best antiglycation and antiaging activity, causing it to contain flavonoid (phenolic group) and tannin content.…”

Section: Oxidasementioning

confidence: 99%

Antioxidant, Antiglycation and in vivo Antiaging Effects of Metabolite Extracts from Marine Sponge-associated Bacteria

Prastya¹,

Astuti²,

Batubara³

et al. 2019

pharmaceutical-sciences

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Marine sponges are evolutionary multicellular organisms that have been reported as the best producers of bioactive compounds, which have antibacterial, antifungal, anticancer and cytotoxic properties [1] . The limitations of sponge biomass and ecological problems such as marine environmental damage and sponge extinction are the main factor for isolating the large scale bioactive compounds. Interestingly, a previous research showed that 40-60 % of sponge biomass is symbiotic microorganisms that can produce metabolite compounds similar to those produced by the host. It is hypothesized that symbiotic marine-microorganisms harbored by sponges are the original producers of these bioactive compounds [2] . Previous studies had revealed the antioxidant and anticancer activity of bacterial crude extracts isolated from sponge Jaspis sp. against human cervix HeLa cells and leukemic cell lines [3,4] . In addition, crude extract of Bacillus sp. isolated from sponge Haliclona sp. was also reported to have anticancer activity against MOLT4 cells and its activity is related to NRPS-PKS genes to encode the bioactive compounds [5] .Antioxidant activity plays an important role in cellular physiology as it has the ability to neutralize and prevent free radicals, including reactive oxygen species (ROS) and its derivatives, from damaging cells. However, an imbalance between ROS production and antioxidant defence may lead to oxidative stress, which may cause degenerative diseases such as cancer, Alzheimer's, cardiovascular, aging and neurological disorders [6] .

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“…Since the action of the enzyme aldose reductase is inhibited by ellagic acid so that the increase in blood glucose can be lowered and the glucose metabolism toward equilibrium. 10…”

Section: Structure Identificationmentioning

confidence: 99%

Isolation of Î‘-Glucosidase Inhibitory Active Compounds From Ethanol Extract of Kayu Tuah (Antidesma Celebicum Miq.) Leaves

Novi¹,

Elya²,

Katrin³

2015

Int. Res. J. Pharm.

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Antidesma celebicum Miq. belongs to Euphorbiaceae family has been used as antidiabetic traditional medicine. The aim of the research was to isolate the α-Glucosidase inhibitory compound from ethanol extract of Antidesma celebicum leaves. The isolation have been done using column chromatography silica gel 60 and the structure was determinated base on spectral data of IR, MS, NMR. The result showed that the isolation obtained gallic acid as α-Glucosidase inhibitor with IC50 value of 0.057 mM.

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REVIEW: Ellagitannin; biosynthesis, isolation, and biological activities

Cited by 6 publications

References 27 publications

PENAMBAHAN EKSTRAK KULIT MANGGIS (Garcinia mangostana. L) DENGAN KOMPOSISI BERBEDA SEBAGAI PEWARNA ALAMI DALAM PENGOLAHAN TERASI BUBUK

PENAMBAHAN EKSTRAK KULIT MANGGIS (Garcinia mangostana. L) DENGAN KOMPOSISI BERBEDA SEBAGAI PEWARNA ALAMI DALAM PENGOLAHAN TERASI BUBUK

Antioxidant, Antiglycation and in vivo Antiaging Effects of Metabolite Extracts from Marine Sponge-associated Bacteria

Isolation of Î‘-Glucosidase Inhibitory Active Compounds From Ethanol Extract of Kayu Tuah (Antidesma Celebicum Miq.) Leaves

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