Review—Intracellular Sensors Based on Carbonaceous Nanomaterials: A Review

Li, Chunmei; Wang, Yihan; Jiang, Hui; Wang, Xuemei

doi:10.1149/1945-7111/ab67a3

Cited by 27 publications

(12 citation statements)

References 152 publications

(179 reference statements)

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“…These carbon-based nanomaterials showed sensitive thermal sensing properties. Additionally, the improvement of metal-free nanoparticles is important and urgent due to the environmental hazard for biological applications for such toxic materials [51,52]. Among the family of carbon-based nanomaterials, fluorescent nanodiamonds have been first reported as nanothermometers [53].…”

Section: Carbon Dots As Nanothermometersmentioning

confidence: 99%

Carbon Dots as New Generation Materials for Nanothermometer: Review

Mohammed

Omer

2020

Nanoscale Res Lett

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Highly sensitive non-contact mode temperature sensing is substantial for studying fundamental chemical reactions, biological processes, and applications in medical diagnostics. Nanoscale-based thermometers are guaranteeing non-invasive probes for sensitive and precise temperature sensing with subcellular resolution. Fluorescence-based temperature sensors have shown great capacity since they operate as “non-contact” mode and offer the dual functions of cellular imaging and sensing the temperature at the molecular level. Advancements in nanomaterials and nanotechnology have led to the development of novel sensors, such as nanothermometers (novel temperature-sensing materials with a high spatial resolution at the nanoscale). Such nanothermometers have been developed using different platforms such as fluorescent proteins, organic compounds, metal nanoparticles, rare-earth-doped nanoparticles, and semiconductor quantum dots. Carbon dots (CDs) have attracted interest in many research fields because of outstanding properties such as strong fluorescence, photobleaching resistance, chemical stability, low-cost precursors, low toxicity, and biocompatibility. Recent reports showed the thermal-sensing behavior of some CDs that make them an alternative to other nanomaterials-based thermometers. This kind of luminescent-based thermometer is promising for nanocavity temperature sensing and thermal mapping to grasp a better understanding of biological processes. With CDs still in its early stages as nanoscale-based material for thermal sensing, in this review, we provide a comprehensive understanding of this novel nanothermometer, methods of functionalization to enhance thermal sensitivity and resolution, and mechanism of the thermal sensing behavior.

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Section: Carbon Dots As Nanothermometersmentioning

confidence: 99%

Carbon Dots as New Generation Materials for Nanothermometer: Review

Mohammed

Omer

2020

Nanoscale Res Lett

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“…Carbon or graphene quantum dots have attracted intensive interest and have also been used to determine biomolecules due to their fascinating properties [ 145 , 146 , 147 , 148 ]. Doping heteroatoms (e.g., nitrogen, sulfur, phosphorus/or metal atoms) in carbon or graphene quantum dots is an effective way to tune their properties [ 107 , 112 , 149 , 150 ].…”

Section: Sulfur-containing Quantum Dotsmentioning

confidence: 99%

Biosensors Based on Advanced Sulfur-Containing Nanomaterials

Wang

Jiang

et al. 2020

Sensors

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In recent years, sulfur-containing nanomaterials and their derivatives/composites have attracted much attention because of their important role in the field of biosensor, biolabeling, drug delivery and diagnostic imaging technology, which inspires us to compile this review. To focus on the relationships between advanced biomaterials and biosensors, this review describes the applications of various types of sulfur-containing nanomaterials in biosensors. We bring two types of sulfur-containing nanomaterials including metallic sulfide nanomaterials and sulfur-containing quantum dots, to discuss and summarize the possibility and application as biosensors based on the sulfur-containing nanomaterials. Finally, future perspective and challenges of biosensors based on sulfur-containing nanomaterials are briefly rendered.

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“…The high mechanical strength, electrical and thermal conductivity [27][28][29] make them ideal as reinforcing elements [30][31][32], as protective materials [33][34][35] and to make conductive polymers [36,37]. Carbon nanomaterials find application also in the biomedical field for sensing applications and in controlled pharmaceuticals and drugs delivery [38][39][40][41][42].…”

Section: Introductionmentioning

confidence: 99%

Carbon Nanomaterials: Synthesis, Functionalization and Sensing Applications

Speranza

2021

Nanomaterials

211

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Recent advances in nanomaterial design and synthesis has resulted in robust sensing systems that display superior analytical performance. The use of nanomaterials within sensors has accelerated new routes and opportunities for the detection of analytes or target molecules. Among others, carbon-based sensors have reported biocompatibility, better sensitivity, better selectivity and lower limits of detection to reveal a wide range of organic and inorganic molecules. Carbon nanomaterials are among the most extensively studied materials because of their unique properties spanning from the high specific surface area, high carrier mobility, high electrical conductivity, flexibility, and optical transparency fostering their use in sensing applications. In this paper, a comprehensive review has been made to cover recent developments in the field of carbon-based nanomaterials for sensing applications. The review describes nanomaterials like fullerenes, carbon onions, carbon quantum dots, nanodiamonds, carbon nanotubes, and graphene. Synthesis of these nanostructures has been discussed along with their functionalization methods. The recent application of all these nanomaterials in sensing applications has been highlighted for the principal applicative field and the future prospects and possibilities have been outlined.

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Review—Intracellular Sensors Based on Carbonaceous Nanomaterials: A Review

Cited by 27 publications

References 152 publications

Carbon Dots as New Generation Materials for Nanothermometer: Review

Carbon Dots as New Generation Materials for Nanothermometer: Review

Biosensors Based on Advanced Sulfur-Containing Nanomaterials

Carbon Nanomaterials: Synthesis, Functionalization and Sensing Applications

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