Review: Micro- and nanosized molecularly imprinted polymers for high-throughput analytical applications

Polymeric nanoparticles for optical sensing

“…Compared to bulk MIPs, the nanosize form has several advantages: it allows the system to exhibit a much higher surface-to-volume ratio and greater total surface area per weight unit of polymer. The imprinted sites are more easily accessible by the templates, thus improving binding kinetics and template removal, and hence enhancing their recognition capabilities (Gao et al, 2007;Tokonami et al, 2009). …”

Placement of Nanospace on an Electrode for Biosensing

“…91 The formation of a nanospace cavity to a target molecule essentially relies on the binding and interaction between constituents and targets. Therefore, a cavity formed in a matrix with a complementary shape and sites for target interaction and binding, provides excellent molecular recognition.…”

Future Applications of Electronic-Nose Technologies in Healthcare and Biomedicine

“…Molecular Imprinted Polymer (MIP) microsensors utilize polymeric materials for the recognition of particular chemical substances that are complementary to a specific receptor cavity. MIP materials usually consist of a copolymerized monomer matrix cross-linked to a template molecule that creates a receptor cavity complimentary to the template molecule when the template is removed from the polymer matrix (Tokonami et al, 2009). These nanostructured MIP objects may be used to develop micro-and nano-sized sensors or sensor arrays for chemical sensing and detection.…”