Review of cytostatic wastewater degradation by ozone and advanced oxidation processes: results from Cuban studies

García, Lidia Asela Fernández; Lozano, O. Ledea; Lorenzo, Eliet Véliz; Venta, Mayra Bataller; Rodríguez, Yalexmi Ramos; Castro, Carlos; Trujillo, C. Gutiérrez; Torres, Irán Fernández

doi:10.1139/er-2018-0109

Cited by 4 publications

(2 citation statements)

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“…AOPs are used today for the treatment of a wide range of contaminants [132][133][134]. These processes are based on the in situ generation of highly reactive species such as reactive oxygen species (ROS), in particular hydroxyl radicals (HO•), H 2 O 2 , O 3 , and superoxide anion radicals (O 2 − ).…”

Section: Advanced Oxidation Processesmentioning

confidence: 99%

“…For instance, the ozonation in buffered and non-buffered solutions at pH 9 and at 303 K using a semi-batch reactor was investigated [123]. Ozone is a highly reactive species and a strong oxidant that is used in degradation of contaminants in industrial WWTP [132]. Isocratic reverse phase high-performance liquid chromatography (RP-HPLC) and electrospray tandem mass spectrometry (ESI-MS/MS) was used for the determination of cisplatin and its reaction products.…”

Section: Advanced Oxidation Processesmentioning

confidence: 99%

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The Dark Side of Platinum Based Cytostatic Drugs: From Detection to Removal

et al. 2021

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The uncontrolled release of pharmaceutical drugs into the environment raised serious concerns in the last decades as they can potentially exert adverse effects on living organisms even at the low concentrations at which they are typically found. Among them, platinum based cytostatic drugs (Pt CDs) are among the most used drugs in cancer treatments which are administered via intravenous infusion and released partially intact or as transformation products. In this review, the studies on environmental occurrence, transformation, potential ecotoxicity, and possible treatment for the removal of platinum cytostatic compounds are revised. The analysis of the literature highlighted the generally low total platinum concentration values (from a few tens of ng L−1 to a few hundred μg L−1) found in hospital effluents. Additionally, several studies highlighted how hospitals are sources of a minor fraction of the total Pt CDs found in the environment due to the slow excretion rate which is longer than the usual treatment durations. Only some data about the impact of the exposure to low levels of Pt CDs on the health of flora and fauna are present in literature. In some cases, adverse effects have been shown to occur in living organisms, even at low concentrations. Further ecotoxicity data are needed to support or exclude their chronic effects on the ecosystem. Finally, fundamental understanding is required on the platinum drugs removal by MBR, AOPs, technologies, and adsorption.

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Section: Advanced Oxidation Processesmentioning

confidence: 99%

Section: Advanced Oxidation Processesmentioning

confidence: 99%