Review on air purifier

Rajapandian, Gowri; Pandiyan, Balaji; Chandrasekar, Leela Priyanka; Krishnan, Kamalesh Raja Gopala; Sebastian, Jenifer; Kesavel, Monica; Sudharsan, Vinoth

doi:10.30574/gscbps.2019.7.1.0038

GSC Biol. and Pharm. Sci.

2019

DOI: 10.30574/gscbps.2019.7.1.0038

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Review on air purifier

Gowri Rajapandian¹,

Balaji Pandiyan²,

Leela Priyanka Chandrasekar³

et al.

Abstract: Air contributes a prime role in recycling earth's most essential substances like carbon, since carbon sources encompass fossil fuel combustion and decayed matter of dead animals. Due to urbanization, population has been increased in cities inevitably which cause dreadful air pollution and pose a profound menace to public health and the environment. Outdoor air pollution has become panic in India, because Indian cities are some of the highest polluted cities in the world. Particulate pollution has significant w… Show more

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2021

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Cited by 2 publications

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Estimation of drug-likeness properties of GC–MS separated bioactive compounds in rare medicinal Pleione maculata using molecular docking technique and SwissADME in silico tools

Sympli

2021

Netw Model Anal Health Inform Bioinforma

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The main aim of the paper was to determine bioactive compounds in Pleione maculata extracts using gas chromatographic technique and to investigate their drug-likeness potential using molecular docking algorithm and ADME studies on the recent intractable disease, for example, SARS-CoV-2. Pleione maculata sample was prepared for GC–MS analysis. The peak components were identified based on the NIST Library. Molecular docking was performed using PatchDock, and energy refinement was carried out using the FireDock algorithm followed by drug-likeness analysis using the SwissADME tool. The mass spectrum revealed various pharmacologically important compounds and novel compounds 8-oxatetracyclo{5.2.1.1(2,6). 1(4,10)}dodecane, 7-tert-butyl-1,9,9-trimeth, docosane, 2,4-dimethyl, kryptogenin 2,4-dinitrophenyl hydrazine, and N -decyl-alpha, D -2-deoxyglycoside which are reported for the first time. Molecular docking using PatchDock illustrates GC–MS compounds Nor-diazepam,3-{ N -hydroxymethyl}aminocarbonyloxy a good docking and high binding affinity with atomic contact energy -10.95 kcal/mol against SARS-CoV-2 spike protein S2 subunit. ADME analysis predicts Nor-diazepam,3-{N-hydroxymethyl}aminocarbonyloxy and andrographolide showed very high drug-likeness parameters with no metabolism disturbances. The random control antiviral drug arabidiol revealed a lower binding affinity and lower solubility compared to bioactive compounds of P. maculata . The study depicts the first and novel report on various pharmaceutical important GC–MS bioactive compounds and molecular docking study on Pleione maculata having potential against various intractable diseases. Supplementary Information The online version contains supplementary material available at 10.1007/s13721-020-00276-1.

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Estimation of drug-likeness properties of GC–MS separated bioactive compounds in rare medicinal Pleione maculata using molecular docking technique and SwissADME in silico tools

Sympli

2021

Netw Model Anal Health Inform Bioinforma

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Green synthesis and biomedicinal applications of silver and gold nanoparticles functionalized with methanolic extract of Mentha longifolia

Rauf

Ahmad

Khan

et al. 2021

Artificial Cells, Nanomedicine, and Biotechnology

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This study deals with facile and rapid synthesis of silver nanoparticles (AgNPs) and Gold nanoparticles (AuNPs) using Mentha longifolia leaves extracts (MLE). The synthesized AgNPs and AuNPs were characterized by UV-visible spectroscopy (UV-Vis), Fourier transformed infra-red spectroscopy (FT-IR), atomic force microscopy (AFM) and transmission electron microscopy (TEM) techniques. The phytochemical analysis showed the presence of bioactive secondary metabolites, which are involved in the synthesis of nanoparticles (NPs). The surface plasmon resonance (SPR) observed at 435 and 550 nm, confirmed the green synthesis of AgNPs and AuNPs, respectively. The TEM images showed poly dispersed and round oval shapes of Ag and Au NPs with an average particles size of 10.23 ± 2 nm and 13.45 ± 2 nm, respectively. TEM results are in close agreements with that of AFM analysis. The FT-IR spectroscopy revealed the presence of OH, -NH 2 and C ¼ O groups, which involved in the synthesis of NPs. The MLE and their AgNPs and AuNP exhibited good in vitro antibacterial and anti-oxidant activities. Moreover, MLE and NPs also showed in vivo analgesic activities in mice, and excellent sedative properties in open field test paradigm.

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Review on air purifier

Cited by 2 publications

References 12 publications

Estimation of drug-likeness properties of GC–MS separated bioactive compounds in rare medicinal Pleione maculata using molecular docking technique and SwissADME in silico tools

Estimation of drug-likeness properties of GC–MS separated bioactive compounds in rare medicinal Pleione maculata using molecular docking technique and SwissADME in silico tools

Green synthesis and biomedicinal applications of silver and gold nanoparticles functionalized with methanolic extract of Mentha longifolia

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