Review on Pharmocological Properties of Aaka (Calotropis procera)

Paul, Amandeep; Kumar, Antul

doi:10.23910/ijep/2018.5.3.0261

Cited by 6 publications

(8 citation statements)

References 7 publications

(7 reference statements)

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“…The whole plant contains α and β amyrin, teraxasterol, gigantin, giganteol, isogiganteol, β-sitosterol, and a wax 14 . Roots of the plant contain triterpenes, a new norditerpenyl ester, named Calotropterpenyl ester, mundarol isovalerate and quercetin -3-rutinoside apentacyclic triterpinoids such as Calotropurseny acetate and calotropfriedelenyl acetate, akundarol isovalerate 15 . The roots are alterative, Anthelmintic, depurative, diaphoretic, emetic, expectorant, febrifuge, and purgative; used to treat anasarca, asthma, ascites, and bronchitis, cough, cutaneous diseases, intestinal worms, leprosy, and eczema 16 .…”

Section: Ijpsr (2022) Volume 13 Issue 3 (Research Article)mentioning

confidence: 99%

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2022

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The Calotropis procera (Ait.) R.Br. (Ascelpidaeaceae) has been used traditionally as anthelmintic, depurative, diaphoretic, emetic, expectorant, febrifuge, and purgative, but no scientific reports are available in the regulation of asthmatic condition. In this present study, Calotropis procera (Ait.) R.Br. was selected to investigate scientifically to establish scientific data for its traditional claim. Materials and Methods: The anti-asthmatic activity of MECP (Methanolic extract of roots of Calotropis procera) and AECP (Aqueous extract of roots of Calotropis procera) was studied by using in-vitro and in-vivo models. The reference drug used was chlorpheniramine (CPM) and Dexamethasone. The in-vitro models included isolated goat tracheal chain and guinea pig ileum preparation. Further, the in-vivo included histamine-induced bronchospasm, milk-induced leukocytosis, passive paw anaphylaxis model, and haloperidol-induced catalepsy. Results: In the in-vitro and in-vivo models, the oral dose of both MECP and AECP showed significant results as compared to control. Among both extracts, MECP showed better activity in the prevention of asthma. Conclusion: Based on phytochemical analysis of the root's extracts of Calotropis procera (Ait.) R.Br showed the presence of alkaloids, steroids, glycosides, flavonoids, tannins, and carbohydrates. The methanolic (MECP) and aqueous (AECP) extracts are effective in all the models of asthma as an order of MECP > AECP except AECP > MECP in isolated guinea pig ileum preparation. Therefore it can be concluded that the plant Calotropis procera (Ait.) R.Br was found to possess potential antiasthmatic activity.INTRODUCTION: Asthma word is derived from a Greek word meaning 'breathless 1 . It is a chronic QUICK RESPONSE CODE

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Section: Ijpsr (2022) Volume 13 Issue 3 (Research Article)mentioning

confidence: 99%

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2022

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“…arbor-tristis leaves have been associated with anti-inflammatory, immunomodulatory, and analgesic effects. Overall, the leaves of both plants offer unique compositions that align with their distinct characteristics and traditional uses. − This study entails a comparison involving the utilization of dried leaf powders to assess their efficiency in methane hydrate formation and storage within the hydrate structure. The impact of these bio powders is juxtaposed against the established surfactant promoter sodium dodecyl sulfate (SDS), as well as the baseline experiment involving pure water.…”

Section: Introductionmentioning

confidence: 99%

Enhancing Methane Storage in Clathrate Hydrates Using Leaf Extract Catalysts: Advancing Sustainable Energy Storage

Ganteda,

Burla,

Boggu

et al. 2023

Energy Fuels

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Gas hydrates have garnered attention for their potential to capture and store large gas volumes in their petite latticelike water structure. This study explores the feasibility of enhancing methane hydrate conversion by hastening hydrate process kinetics, maximizing methane uptake, and storage using benign additives sourced from dried leaves of Calotropis procera (CTP) (milkweed) and Nyctanthes arbor-tristis (NA) (night-flowering jasmine). These bioadditives were compared with the well-known methane hydrate former sodium dodecyl sulfate (SDS) and pure water as a baseline. Methane hydrate formation occurred at approximately 271.7 ± 0.78 K with bioadditives, whereas SDS exhibited formation at around 278.15 ± 1.37 K under stirred and nonstirred conditions. Bioadditives required twice the subcooling of the SDS system, and the methane uptake kinetics were faster in nonstirred conditions and doubled under stirring. Overall methane captured with the selected additives was similar to that of SDS, with slightly higher uptake under stirring. These bioextracts displayed favorable methane hydrate affinity, attributed to mixed constituents including alkaloids, flavonoids, cardenolides, carotenoids, and phenolic compounds. These additives, which are biodegradable and less toxic, stand as eco-friendly alternatives to organic agents like SDS. Offering nonfoaming properties for smoother operations and reusability, bioadditives hold promise for sustainable applications.

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“…A recent study recommends the use of C. procera leaves extract as an alternative milk coagulant because of the presence of the calotropin enzyme in it and there is no toxicity found even at higher doses (Abebe & Emire, 2020 ). This plant has also been found to be associated with neuroprotection in neurodegenerative diseases, that is, Alzheimer's disease by attenuating the accumulation of amyloid‐beta proteins in neuronal tissues (Paul et al., 2018 ). Crude leaves powder has been documented to be used relieving joint pain and reducing inflammation (Meena et al., 2011 ).…”

Section: Introductionmentioning

confidence: 99%