Review on safety of the entomopathogenic fungi<i>Beauveria bassiana</i>and<i>Beauveria brongniartii</i>

Zimmermann, G.

doi:10.1080/09583150701309006

Cited by 593 publications

(380 citation statements)

References 205 publications

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“…In one study, 5 of 16 B. bassiana strains freshly isolated from insect hosts were found to be capable of producing oosporein under the conditions tested; however, the oosporein-producing strains lost their ability to synthesize the red pigment after serial passage on artificial media (15). Nonetheless, it has been noted that insect cadavers killed by B. bassiana appear reddish immediately at death (16). Several studies have indicated that oosporein may possess some insecticidal activity.…”

mentioning

confidence: 99%

Regulatory cascade and biological activity of Beauveria bassiana oosporein that limits bacterial growth after host death

Fan

Liu

Keyhani

et al. 2017

Proc. Natl. Acad. Sci. U.S.A.

124

119

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The regulatory network and biological functions of the fungal secondary metabolite oosporein have remained obscure. Beauveria bassiana has evolved the ability to parasitize insects and outcompete microbial challengers for assimilation of host nutrients. A novel zinc finger transcription factor, BbSmr1 (B. bassiana secondary metabolite regulator 1), was identified in a screen for oosporein overproduction. Deletion of Bbsmr1 resulted in up-regulation of the oosporein biosynthetic gene cluster (OpS genes) and constitutive oosporein production. Oosporein production was abolished in double mutants of Bbsmr1 and a second transcription factor, OpS3, within the oosporein gene cluster (ΔBbsmr1ΔOpS3), indicating that BbSmr1 acts as a negative regulator of OpS3 expression. Real-time quantitative PCR and a GFP promoter fusion construct of OpS1, the oosporein polyketide synthase, indicated that OpS1 is expressed mainly in insect cadavers at 24-48 h after death. Bacterial colony analysis in B. bassiana-infected insect hosts revealed increasing counts until host death, with a dramatic decrease (∼90%) after death that correlated with oosporein production. In vitro studies verified the inhibitory activity of oosporein against bacteria derived from insect cadavers. These results suggest that oosporein acts as an antimicrobial compound to limit microbial competition on B. bassiana-killed hosts, allowing the fungus to maximally use host nutrients to grow and sporulate on infected cadavers.Beauveria bassiana | oosporein | biological role | transcription factor | fungal-bacterial competition

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mentioning

confidence: 99%

Regulatory cascade and biological activity of Beauveria bassiana oosporein that limits bacterial growth after host death

Fan

Liu

Keyhani

et al. 2017

Proc. Natl. Acad. Sci. U.S.A.

124

119

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“…High temperatures normally decrease the viability of fungal spores (Zimmermann 2007), which explains why fewer spores germinated after incubating the fungal spores at 33°C for 15 days, than at 10 or 5 days, before being transferred to 25°C. This is consistent with the report that exposure to a high temperature for a longer time caused a lower germination rate, and that at over 36°C no spores germinated (Shimazu 2004).…”

Section: Discussionmentioning

confidence: 99%

“…For example, isolate ICIPE278 caused a higher mortality at 25°C than ICIPE279, but this was vice versa at 30°C, where the mutant isolate adjusted itself better than the WT isolate under stable greenhouse conditions (35.0±2.5°C). The efficiency of fungal pathogenicity is known to involve many factors, including spore germination efficiency, hyphal growth and sporulation (Zimmermann 2007).…”

Section: Discussionmentioning

confidence: 99%

“…Temperature, humidity and solar radiation are all important factors for fungal growth, germination and viability (Zimmermann 2007). Climate change has a serious impact on the environment, including drought and higher temperatures, which can affect the fungal pathogenicity by reducing activities of the fungus before contacting its host or by reducing fungal growth within the host (Zimmermann 2007). Moreover, prolonged exposure to the sun's rays reduces the fungal viability and its sporulation.…”

Section: Introductionmentioning

confidence: 99%

“…The fungus has a reported optimum temperature of around 25°C for hyphal growth (Hallsworth and Magan 1999;Tefera and Pringle 2003), while the highest pathogenicity against Diatraea saccharalis was reported to be at 26°C (Svedese et al 2013). Temperature, humidity and solar radiation are all important factors for fungal growth, germination and viability (Zimmermann 2007). Climate change has a serious impact on the environment, including drought and higher temperatures, which can affect the fungal pathogenicity by reducing activities of the fungus before contacting its host or by reducing fungal growth within the host (Zimmermann 2007).…”

Section: Introductionmentioning

confidence: 99%

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Development of thermotolerant isolates of Beauveria bassiana (Bals.-Criv.) Vuill. with ethyl methanesulfonate

Wongwanich

Cobelli

Boonchuay³

et al. 2018

Journal of Plant Protection Research

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Beauveria bassiana is an entomopathogenic fungus that is widely used in Thailand to control pest insects. However, the increasing temperature has influenced the insect control efficiency of the fungus. Therefore, determination of thermotolerant isolates of B. bassiana that can grow and remain pathogenic at higher temperatures than its current optimum temperature may be a better way to control pest insects in a high temperature environment. Three isolates of B. bassiana obtained from the Rice Department, Thailand were selected for mutagenesis using ethyl methanesulfonate (EMS) with subsequent screening at high temperatures (33 and 35°C). In addition, the recovery of fungal growth after exposure to a high temperature for a period of time (5-15 days) and then transferring to 25°C was evaluated. No isolates were found that grew at 35°C but one mutant isolate (BCNT002MT) produced larger diameter colonies and more spores than the corresponding wild type (WT) at 33°C. Growth and spore production of the BCNT002MT isolate were greater than its WT when incubated at 25°C for 14 days following exposure to 33°C for 7 days. In addition, the spore germination level (%) of BCNT002MT was significantly higher than its WT during culture at 25°C after prior exposure to 33°C for 5, 10 and 15 days. The pathogenicity against the brown planthopper, Nilaparvata lugens (Stål), of this mutant isolate was also prominent.

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Entomopathogens

Bara¹,

Laing²

2019

Horticultural Reviews

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Review on safety of the entomopathogenic fungiBeauveria bassianaandBeauveria brongniartii

Cited by 593 publications

References 205 publications

Regulatory cascade and biological activity of Beauveria bassiana oosporein that limits bacterial growth after host death

Regulatory cascade and biological activity of Beauveria bassiana oosporein that limits bacterial growth after host death

Development of thermotolerant isolates of Beauveria bassiana (Bals.-Criv.) Vuill. with ethyl methanesulfonate

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