Review: The approaches for estimation of limit of detection for ICP-MS trace analysis of arsenic

In the ‘Vocabulaire International de Métrologie’ (VIM) as published by the ‘Bureau International des Poids et Mésures’ (BIPM) the term ‘metrology’ is defined as “the science of measurement and its application” and covers all theoretical and practical aspects of any measurement, including uncertainty and field of application. This book chapter on metrology summarizes the basic metrological terminology related to inorganic sector field mass spectrometry. General terminology and explanatory notes on terms related to e.g. validation, uncertainty and calibration is given, where VIM-based terminology is compared to and supplemented by IUPAC-based definitions and recommendations. A compact overview about the most relevant metrological institutions worldwide is given in order to provide insight into the organization of metrological network institutions. Metrological traceability, which is required for the establishment of a calibration hierarchy, providing that all input parameters into a model equation are traceable to a common reference (e.g. the SI-unit) is defined together with related aspects such as the use of reference materials. The principle of the estimation of a sound measurement uncertainty is presented. This book chapter should contribute to the mutual understanding of metrological terminology being used within the scientific community.

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“…Details about these approaches have been discussed extensively in the literature. [6][7][8][9][10][11] …”

Section: Limit Of Quantification/quantification Limit (Loq)mentioning

confidence: 99%

Metrology

Irrgeher

Prohaska

2014

Sector Field Mass Spectrometry for Elemental and Isotopic Analysis

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“…LoD for an analyte is the lowest mass or concentration that an analytical procedure can determine with a reasonable confidence level for the analyte [25]. To determine the LoD, a method of triple standard deviation (SD) is usually used [26].…”

Section: Limits Of Detection (Lod) and Limits Of Quantification (Loq)mentioning

confidence: 99%

Validation and Application of Ultrasound-assisted Extraction Coupled with ICP-MS for Determination of Toxic Metals in Fine Particles

Liang¹,

Ding²,

Ma³

et al. 2017

JRST

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analysis of chemical compositions of fine particle matters (PM 2.5 ) in contaminated atmospheres has increasingly become a great concern of both scientific and technological importance because the contaminant concentrations of PM 2.5 are playing an important role in affecting PM 2.5 -induced adverse effects on environment and human health. In this paper, ultrasound-assisted extraction coupled with ICP-MS was developed for a simultaneous quantification of 12 toxic elements (Be, al, Cr, Mn, Ni, as, Se, Sb, Tl, Pb, Hg and Cd) in PM 2.5 samples. The proposed method was validated with several parameters, namely linearity of calibration, precision and accuracy, limit of detection (LOD) and limit of quantification (LOQ). The accuracy of the proposed method was validated with recovery tests of different samples spiked with corresponding elements at known concentrations (5, 10 and 20 μg/L) and the average percent recovery varied in the range of 87.3-101.3%. The results showed that this method was a multi-element technique featuring high precision and accuracy as well as low LOD. This proposed method was applied to a simultaneous determination of the 12 target elements in atmospheric fine particles collected from a heavily polluted urban residential area in China, and showed that the particles were rich in al, Pb and Mn, followed by as, Sb, Cr, Cd, Se and Ni. The main advantages of the ultrasound-assisted extraction process were fast sample treatment and low consumption of reagents in the extraction process.

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“…D'Ilio et al 117 report and discuss the most common causes of interference found in As measurements, with proposals for correction. Rajaković et al 118 report a study focused on estimating the limits of detection (LOD) for arsenic at trace levels, when using ICP-MS. The authors review current approaches and discuss them, supporting the conclusions with their experimental work.…”

Section: Techniques Involving Direct Measurementmentioning

confidence: 99%

Inorganic Arsenic Determination in Food: A Review of Analytical Proposals and Quality Assessment Over the Last Six Years

2016

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Here we review recent developments in analytical proposals for the assessment of inorganic arsenic (iAs) content in food products. Interest in the determination of iAs in products for human consumption such as food commodities, wine, and seaweed among others is fueled by the wide recognition of its toxic effects on humans, even at low concentrations. Currently, the need for robust and reliable analytical methods is recognized by various international safety and health agencies, and by organizations in charge of establishing acceptable tolerance levels of iAs in food. This review summarizes the state of the art of analytical methods while highlighting tools for the assessment of quality assessment of the results, such as the production and evaluation of certified reference materials (CRMs) and the availability of specific proficiency testing (PT) programmes. Because the number of studies dedicated to the subject of this review has increased considerably over recent years, the sources consulted and cited here are limited to those from 2010 to the end of 2015.

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Review: The approaches for estimation of limit of detection for ICP-MS trace analysis of arsenic

Cited by 74 publications

References 21 publications

Metrology

Metrology

Validation and Application of Ultrasound-assisted Extraction Coupled with ICP-MS for Determination of Toxic Metals in Fine Particles

Inorganic Arsenic Determination in Food: A Review of Analytical Proposals and Quality Assessment Over the Last Six Years

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