Mosques, aside from serving as places of worship for Muslims, also function as institutions for education, social interaction, economic activities, and community empowerment. However, in reality, many mosques only serve as “ivory towers” amidst community life, limited to religious roles such as places of worship and religious instruction. This article aims to discuss the revitalization of the mosque’s role as a center for community empowerment through a systemic approach. The research method applied is qualitative, utilizing a literature review model. The data used is derived from a review of relevant literature focused on the research objectives. The findings of this study indicate that the revitalization of the mosque’s role requires a systemic approach, where mosques establish strategic partnerships with external institutions in spiritual, intellectual, social, and economic aspects. Human resource development and economic collaboration with economic development institutions are identified as crucial elements. Synergistic coordination in mosque management, through the formation of specialized teams at the high level, divisions at the mid-level, and implementation teams at the lower level, is viewed as a crucial step to ensure the effective management and implementation of programs. This study emphasizes that through a systemic approach, mosques can play an integral role in holistic community empowerment, making the systemic approach a necessity in revitalizing the mosque’s role as a center for community empowerment.