Revolutionizing anticancer treatment: Ruthenium-based nanoplatforms pave new paths

Karati, Dipanjan; Meur, Shreyasi; Mukherjee, Swarupananda; Roy, Souvik

doi:10.1016/j.ccr.2024.216118

Coordination Chemistry Reviews

2024

DOI: 10.1016/j.ccr.2024.216118

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Revolutionizing anticancer treatment: Ruthenium-based nanoplatforms pave new paths

Dipanjan Karati,

Shreyasi Meur,

Swarupananda Mukherjee

et al.

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Cited by 3 publications

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Research Progress of Endoplasmic Reticulum Targeting Metal Complexes in Cancer Therapy

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Wu,

Zhu

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Drug Development Research

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The development of anticancer drugs that target different organelles has received extensive attention due to the characteristics of cancer recurrence, metastasis, and drug resistance. The endoplasmic reticulum (ER) is an important structure within the cell that is primarily responsible for protein synthesis, folding, modification, and transport and plays a crucial role in cell function and health. ER stress activation induces cancer cell apoptosis. New anticancer drugs with different anticancer mechanisms and selectivity can be designed because of redox activity, composition diversity, and metal complexes structure regulation. Over the past few decades, dozens of metal complexes have killed cancer cells through ER stress, showing powerful tumor‐suppressive effects. This review summarizes the progress of research on anticancer metallic drugs that induce ER stress over the past few years, which is expected to bring more breakthroughs in the field of medicine and life science.

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Research Progress of Endoplasmic Reticulum Targeting Metal Complexes in Cancer Therapy

Xu,

Wu,

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et al. 2024

Drug Development Research

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Revolutionizing anticancer treatment: Ruthenium-based nanoplatforms pave new paths

Cited by 3 publications

References 222 publications

Research Progress of Endoplasmic Reticulum Targeting Metal Complexes in Cancer Therapy

Research Progress of Endoplasmic Reticulum Targeting Metal Complexes in Cancer Therapy

Advancements in platinum-based anticancer drug development: A comprehensive review of strategies, discoveries, and future perspectives

Synthesis and evaluation of amyloid beta peptide/Ruthenium III-based complex drugs as drug delivery and anticancer activity

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