RGD-targeted redox responsive nano micelle: co-loading docetaxel and indocyanine green to treat the tumor

Ren, Lili; Nie, Junfang; Wei, Jie; Li, Yaning; Yin, Jun; Yang, Xiaolong; Chen, Guoguang

doi:10.1080/10717544.2021.1977425

Cited by 13 publications

(8 citation statements)

References 46 publications

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“…Combinational therapy improved photodestruction without tumour recurrence over photothermal therapy (PTT) or photodynamic therapy (PDT) alone. Ren [10] created a disulfide bond block copolymer to overcome issues regarding the properties of ICG and its therapeutic potential. The polymer employs RGD peptide (ar-arginine-glycineaspartic acid) as the active targeting group, PEG (polyethylene glycol) as the hydrophilic end, and PCL (polycaprolactone) as the hydrophobic end.…”

Section: Resultsmentioning

confidence: 99%

Indocyanine Green(Icg) And Colorectal Surgery: A Literature Review on Qualitative and Quantitative Methods of Usage

Simion¹,

Ionescu²,

Chitoran³

et al. 2023

Preprint

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Background: This literature review investigates qualitative and quantitative uses of indocyanine green (ICG) in surgical treatment, as this novel technique has become increasingly popular in ORs (operating rooms) worldwide due to its many advantages. Method: An extensive literature review was performed by searching for relevant terms in 5 international databases (www.pubmed.gov, www.sciencedirect.com, www.scopus.com, www.Oxfordjournals.com, www.reaxys.com). The results of this search were summarized into the main advantages of employing ICG in colorectal surgery as follows: a) intraoperative fluorescence angiography capability; b) fluorescence-guided identification of lymph node involvement in colorectal cancer and the sentinel lymph node method; c) positive fluorescence flagging of a liver tumour as small as "only" 200 tumour cells; d) facilitation of fistula diagnosis; and e) tumour tattooing. Moreover, in addition to qualitative intraoperative ICG use, this technique can be combined with quantitative methods and parameters, such as maximum intensity, relative maximum intensity, and different inflow parameters (time-to-peak, slope, and t1/2max). The conclusion of this article is that fluorescence surgery with ICG aided by near-infrared (NIR) light is a relatively recent technology, an advantage of which is improving the specific anatomic and functional information provided, thus allowing more comprehensive and safer tumour removal as well as preservation of important structures.

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Section: Resultsmentioning

confidence: 99%

Indocyanine Green(Icg) And Colorectal Surgery: A Literature Review on Qualitative and Quantitative Methods of Usage

Simion¹,

Ionescu²,

Chitoran³

et al. 2023

Preprint

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“…In situ-created photothermal network-based thermosensitive hydrogel (PNT-gel) from supramolecular cross-linking conjugated polymers stabilizes ICG and offers excellent combinatorial photothermal/photodynamic anticancer therapy. Ren [ 10 ] created a disulfide bond block copolymer to overcome issues regarding the properties of ICG and its therapeutic potential. The amphiphilic polymer delivered DOC (docetaxel) and ICG (indocyanine green) for photothermal chemotherapy.…”

Section: Methodsmentioning

confidence: 99%

Indocyanine Green (ICG) and Colorectal Surgery: A Literature Review on Qualitative and Quantitative Methods of Usage

Simion,

Ionescu,

Chitoran

et al. 2023

Medicina

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Background: Due to its many benefits, indocyanine green (ICG) has gained progressive popularity in operating rooms (ORs) globally. This literature review examines its qualitative and quantitative usage in surgical treatment. Method: Relevant terms were searched in five international databases (1. Pubmed, 2. Sciencedirect, 3. Scopus, 4. Oxfordjournals, 5. Reaxys) for a comprehensive literature review. The main benefits of using ICG in colorectal surgery are: intraoperative fluorescence angiography; fluorescence-guided lymph node involvement detection and the sentinel technique; the fluorescent emphasis of a minute liver tumour, counting just 200 tumour cells; facilitation of fistula diagnosis; and tumour tattooing. This methodology can also be used with quantitative characteristics such as maximum intensity, relative maximum intensity, and in-flow parameters such as time-to-peak, slope, and t1/2max. This article concludes that fluorescence surgery with ICG and near-infrared (NIR) light is a relatively new technology that improves anatomical and functional information, allowing more comprehensive and safer tumour removal and the preservation of important structures.

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“…It is worth noting that premature drug leakage, low drug delivery efficiency and defective cellular uptake are considerable (Almawash et al, 2018), breast cancer (Lu et al, 2020), and prostate cancer (Xiao et al, 2022). In addtion, glycol chitosan (GC)-based polymeric nanoagents have been widely used for delivering chemotherapeutic drugs via hydrophobic interactions, such as paclitaxel (Hao et al, 2019), cisplatin (Wang et al, 2021), camptothecin (CPT) (Dutta et al, 2021), or DTX (Ren et al, 2021), resulting in maximized therapeutic efficacies.…”

Section: The Role Of Novel Polymeric Nanoagents In Cancer Treatmentmentioning

confidence: 99%

Development of novel polymeric nanoagents and their potential in cancer diagnosis and therapy runing title: Polymeric nanoagents for cancer theranostics

et al. 2022

Front. Chem.

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Cancer has been one of the leading factors of death around the world. Cancer patients usually have low 5-year survival rates and poor life quality requiring substantial improvement. In clinic, the presenting diagnostic strategies lack sensitivity with only a small proportion of patients can be accurately identified. For diagnosed patients, most of them are at the advanced stages thus being delayed to receive treatment. Therefore, it is eager to investigate and develop highly effective and accurate techniques for cancer early diagnosis and individualized therapy. Various nanoplatforms are emerging as imaging agents and drug carriers for cancer theranostics recently. Novel polymeric nanoagents, as a potent exemplar, have extraordinary merits, such as good stability, high biosafety and high drug loading efficacy, showing the great prospect for cancer early diagnosis and precise treatment. Herein, we review the recent advances in novel polymeric nanoagents and elucidate their synthesis procedures. We further introduce the applications of novel polymeric nanoagents in cancer diagnosis, treatment, and theranostics, as well as associated challenges and prospects in this field.

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RGD-targeted redox responsive nano micelle: co-loading docetaxel and indocyanine green to treat the tumor

Cited by 13 publications

References 46 publications

Indocyanine Green(Icg) And Colorectal Surgery: A Literature Review on Qualitative and Quantitative Methods of Usage

Indocyanine Green(Icg) And Colorectal Surgery: A Literature Review on Qualitative and Quantitative Methods of Usage

Indocyanine Green (ICG) and Colorectal Surgery: A Literature Review on Qualitative and Quantitative Methods of Usage

Development of novel polymeric nanoagents and their potential in cancer diagnosis and therapy runing title: Polymeric nanoagents for cancer theranostics

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