Rhabdomyolysis associated with influenza A/H1N1 2009 infection in a pediatric patient

Abstract

The influenza A/H1N1 2009 epidemic has spread to many countries since 2009, including Japan. We report an immune-competent child involving rhabdomyolysis and compartment syndrome associated with influenza A/H1N1 2009. The patient was demonstrated rhabdomyolysis with myoglobinuria, hyperkalemia, cardiac dysfunction and compartment syndrome that arose during convalescence from influenza A/H1N1 2009 infection. Although RT-PCR of muscle tissue yielded negative results for influenza A/H1N1 2009 RNA and no viral positive-antigen cells were detected in the muscle lesions, the clinical picture suggested rhabdomyolysis associated with influenza A/H1N1. Rhabdomyolysis should be considered in the evaluation of muscle symptoms such as myalgia associated with novel influenza A/H1N1 2009 virus infection, particularly in critically ill patients.

Recurrent rhabdomyolysis in a child. Case presentation

“…10,11 Prednisolone and intravenous immunoglobulinare other treatment options. 12 We used fluid resuscitation, administering diuretics and sodium bicarbonate in the all hospitalization of our case. We also used prednisolone and intravenous immunoglobulin in the first hospitalization ofo ur patient.…”