Rhabdomyolysis Associated with Parainfluenza Virus

Douvoyiannis, Miltiadis; Kielbasa, Johanna M.; Chandrasekharan, Gopal; Holmes, Cynthia L.; Gomez, Michael R.

doi:10.1155/2013/650965

Cited by 8 publications

(9 citation statements)

References 14 publications

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“…Risk factors for developing rhabdomyolysis include myalgia, arterial hypertension, and acute renal failure . More rarely rhabdomyolysis may be triggered by infections with influenza‐A , influenza‐B , parainfluenza , herpes‐6 , varicella zoster , cytomegaly virus (CMV) , coronavirus‐NL63 , chikungunya , Alkhurma hemorrhagic fever virus , or HIV‐1 . Rhabdomyolysis in dengue fever infections can be life‐threatening in some cases .…”

Section: Resultsmentioning

confidence: 99%

Secondary myopathy due to systemic diseases

et al. 2016

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Section: Resultsmentioning

confidence: 99%

Secondary myopathy due to systemic diseases

et al. 2016

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“…15,16 Rhabdomyolysis-induced kidney injury is most commonly associated with influenza as well as other causes, including coxsackie virus, human immunodeficiency virus, and parainfluenza. 17,18 The presence of AKI in our cohort was based on ICD-9 coding; thus, we were unable to evaluate for the possible cause or classification of AKI. The mean degree of change in serum creatinine and estimated glomerular filtration rate among our subjects with AKI is consistent with AKI defined by either the KIDGO group (creatinine increase of 0.3 mg/dL or 150-200% of baseline, or urine output < 0.5 mL/kg/h for 6 h) or the modified RIFLE criteria (decrease in estimated glomerular filtration rate of 25% or urine output < 0.5 mL/kg/h for 8 h).…”

Section: Discussionmentioning

confidence: 99%

Human Metapneumovirus Infection in Hospitalized Children

et al. 2020

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BACKGROUND: Most children are exposed to human metapneumovirus (HMPV) by the age of 5 y. This study aimed to describe the morbidity associated with HMPV infections in a cohort of children in the Midwest of the United States. METHODS: This was a retrospective 2-center cohort study including children (0-17 y old) hospitalized with HMPV infections at 2 tertiary care pediatric hospitals from 2009 to 2013. Demographics, chronic medical conditions, viral coinfections, and hospitalization characteristics, including the need for respiratory support, highflow nasal cannula, CPAP, bi-level positive airway pressure, invasive mechanical ventilation, pediatric ICU admission, acute kidney injury (AKI), use of extracorporeal membrane oxygenation, and length of stay, were collected. RESULTS: In total, 131 subjects were included. Those with one or more comorbidities were older than their otherwise healthy counterparts, with a median age of 2.8 y (interquartile range [IQR] 1.1-7.0) compared to 1.3 y (IQR 0.6-2.0, P < .001), respectively. Ninety-nine (75.6%) subjects required respiratory support; 72 (55.0%) subjects required nasal cannula, simple face mask, or tracheostomy mask as their maximum support. Additionally, 1 (0.8%) subject required high-flow nasal cannula, 1 (0.8%) subject required CPAP, 2 (1.5%) subjects required bi-level positive airway pressure, 15 (11.5%) subjects required invasive mechanical ventilation, 4 (3.1%) subjects required high-frequency oscillatory or jet ventilation, and 4 (3.1%) subjects required extracorporeal membrane oxygenation. Fifty-one (38.9%) subjects required pediatric ICU admission, and 16 (12.2%) subjects developed AKI. Subjects with AKI were significantly older than those without AKI at 5.4 y old (IQR 1.6-11.7) versus 1.9 y old (IQR 0.7-3.5, P 5 .003). After controlling for the presence of at least one comorbidity and cystic fibrosis, each year increase in age led to a 16% increase in the odds of AKI (P 5 .01). The median length of stay for the entire cohort was 4.0 d (IQR 2.7-7.0).

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“…However, some researchers have attributed the term "benign myositis" to simple cases of muscle pain and inflammation, in combination with a rise in CPK level; the term "rhabdomyolysis" is used when myoglobinuria is added to this combination (10,11). It should be emphasized that calf pain without a rise in CPK level is not myositis, but an uncommon symptom of viral infections such as influenza (12).…”

Section: Discussionmentioning

confidence: 99%

“…As mentioned earlier, there are different types of viruses which may cause myositis or rhabdomyolysis. In addition, Douvoyiannis et al introduced the case of a seven-year-old boy diagnosed with rhabdomyolysis, associated with parainfluenza virus (10). Moreover, over a one-year period, Rajajee and colleagues reported 40 cases of myositis in whom Guillain-Barre syndrome was the most common referral diagnosis (5).…”

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confidence: 99%

An Unusual Cause of Limping in Childhood: Lessons from H1N1 Influenza Case Series

Sedighi

Nouri

Sadrosadat

2016

Arch Clin Infect Dis

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Introduction: Identification of the etiology of limping and gait disturbances in children necessitates accurate physical examination and history taking. Although serious conditions such as septic arthritis and Guillain-Barre syndrome are usually prioritized in the differential diagnosis of limping, benign disorders such as benign acute childhood myositis (BACM) should not be discarded. Case Presentation: During the recent H1N1 influenza pandemic in the fall and winter of 2015 -2016 in Hamadan, Iran, three school children presented to our clinic with limping and abnormal gait. Precise history taking, in addition to accurate physical examination and simple laboratory tests, confirmed the diagnosis of myositis. The patients were discharged soon after complete recovery.

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Rhabdomyolysis Associated with Parainfluenza Virus

Cited by 8 publications

References 14 publications

Secondary myopathy due to systemic diseases

Secondary myopathy due to systemic diseases

Human Metapneumovirus Infection in Hospitalized Children

An Unusual Cause of Limping in Childhood: Lessons from H1N1 Influenza Case Series

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