Rhabdomyomatous mesenchymal hamartoma presenting as a skin tag in a newborn

Fontecilla, Natalia M.; Weitz, Nicole A.; Day, Christina; Golas, Alyssa R.; Grossman, Marc E.; Reiffel, Robert S.

doi:10.1016/j.jdcr.2016.03.013

Cited by 8 publications

(15 citation statements)

References 8 publications

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“…Fetal rhabdomyoma, neuromuscular hamartoma, embryonal rhabdomyosarcoma, and rhabdomyomatous mesenchymal hamartoma all contain skeletal elements in the dermis and/or subcutaneous tissue. However, in rhabdomyomatous mesenchymal hamartoma, the striated muscle is well differentiated and randomly arranged with adnexal structures, blood vessels and peripheral nerves [ 2 ]. In fetal rhabdomyoma, there are less differentiated and denser muscular elements.…”

Section: Discussionmentioning

confidence: 99%

“…Rhabdomyomatous mesenchymal hamartoma is a congenital skin mass which was first described as a mesenchymal hamartoma with striated muscle in 1986 [ 1 ]. Since its first report, 66 more cases have been reported in the literature [ 2 ]. It is dermal and subcutaneous lesion which exhibit an abnormal arrangement of mesenchymal elements and prominence of skeletal muscle.…”

Section: Introductionmentioning

confidence: 99%

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Rhabdomyomatous Mesenchymal Hamartoma Presenting as a Midline Mass on a Chin

Kim

Chung

Sung

et al. 2017

Arch Craniofac Surg

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Rhabdomyomatous Mesenchymal Hamartoma Presenting as a Midline Mass on a Chin

Kim

Chung

Sung

et al. 2017

Arch Craniofac Surg

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“…STH most commonly presents in the head and neck as in our cases (11 cases, 91.7%) specifically in the midline chin region 14,37,42,46,57,58,62 . Only one of our cases presented outside of the head and neck region, specifically in the perineum as an inflamed skin tag.…”

Section: Discussionmentioning

confidence: 53%

“…STH most commonly presents in the head and neck as in our cases (11 cases, 91.7%) specifically in the midline chin region. 14,37,42,46,57,58,62 Only one of our cases presented outside of the head and neck region, specifically in the perineum as an inflamed skin tag. Moreover, several reports of cases presenting outside the head and neck region where the specific locations include the perineum, vagina, sacrum, lower back and buttock, and hand.…”

Section: Striated Muscle Hamartomamentioning

confidence: 85%

“…Histopathologically the lesions were characterized by striated muscle proliferation on the dermis. Since then more than 60 cases have been reported in the literature, with a preference for pediatric patients, especially for newborns and infants, arguing for a true congenital nature to this lesion 13,36‐58 . To date, the largest case series described five cases, with three cases presenting in the pediatric age and the remaining two cases presenting in a 48‐ and a 54‐year‐old patients 14 .…”

Section: Discussionmentioning

confidence: 99%

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Smooth muscle hamartoma and striated muscle hamartoma: Clinicopathologic characterization of two rare entities and literature review

González

Dehner

2020

J Cutan Pathol

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Smooth muscle hamartoma (SMH) and striated muscle hamartoma (STH) are anomalous proliferations of smooth muscle or striated muscle, respectively, in anatomic sites where these tissues are normally present. To date, only limited cases have been reported describing these lesions. In this study, we sought to characterize the clinicopathologic features of both SMH and STH. A total of 27 cases of SMH and 12 cases of STH from 1990 to 2020 were identified. SMH cases had a slight male predominance (63%) and a mean age of presentation of 20 years (range: 4 months‐91 years), with a mean size of 9.3 mm (±13.3). In contrast, STH were equally distributed in gender, with a mean age of presentation of 40 years (range: 3 months‐66 years) and a mean size of 5.7 mm (±3.6). SMH were more commonly located in the torso and extremities (70%) and STH in the head and neck area (92%). One case of SMH recurred after 1.1 years and in the initial diagnosis the lesion was present at the tissue edge. None of the cases of STH had a recurrence. We present the largest cohort of SMH and STH, and report the first case of a recurrent SMH, suggesting the importance of obtaining a clean margin for these lesions.

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